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Neil M Nathanson

Explore the profile of Neil M Nathanson including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 1367
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Recent Articles
1.
Lehner K, Silverman H, Addorisio M, Roy A, Al-Onaizi M, Levine Y, et al.
Front Immunol . 2019 Apr; 10:585. PMID: 31024522
The brain regulates physiological functions integral to survival. However, the insight into brain neuronal regulation of peripheral immune function and the neuromediator systems and pathways involved remains limited. Here, utilizing...
2.
Carr B, Mihara K, Ramachandran R, Saifeddine M, Nathanson N, Stell W, et al.
Invest Ophthalmol Vis Sci . 2018 Jun; 59(7):2778-2791. PMID: 29860464
Purpose: Myopia is a refractive disorder that degrades vision. It can be treated with atropine, a muscarinic acetylcholine receptor (mAChR) antagonist, but the mechanism is unknown. Atropine may block α-adrenoceptors...
3.
Kow R, Cheng E, Jiang K, Le J, Stella N, Nathanson N
Pharmacol Res Perspect . 2015 Feb; 3(1):e00100. PMID: 25692018
One of the major signs of severe organophosphate poisoning is seizures. Previous studies have shown that both muscarinic agonist- and organophosphate-induced seizures require activation of muscarinic acetylcholine receptors in the...
4.
Melone M, Pellegrino M, Nolano M, Habecker B, Johansson S, Nathanson N, et al.
Ann Clin Transl Neurol . 2014 Dec; 1(11):926-32. PMID: 25540807
A woman was isozygous for a novel mutation in the leukemia inhibitory factor receptor gene (LIFR) (c.2170C>G; p.Pro724Ala) which disrupts LIFR downstream signaling and results in Stüve-Wiedemann syndrome (STWS). She...
5.
Yi F, Ball J, Stoll K, Satpute V, Mitchell S, Pauli J, et al.
J Physiol . 2014 Jun; 592(16):3463-94. PMID: 24879872
Parvalbumin-containing (PV) neurons, a major class of GABAergic interneurons, are essential circuit elements of learning networks. As levels of acetylcholine rise during active learning tasks, PV neurons become increasingly engaged...
6.
Kow R, Jiang K, Naydenov A, Le J, Stella N, Nathanson N
PLoS One . 2014 Apr; 9(4):e95922. PMID: 24752144
Administration of the muscarinic agonist pilocarpine is commonly used to induce seizures in rodents for the study of epilepsy. Activation of muscarinic receptors has been previously shown to increase the...
7.
Kow R, Nathanson N
Nature . 2012 Feb; 482(7386):480-1. PMID: 22358836
No abstract available.
8.
Nathanson N
Neurochem Int . 2012 Feb; 61(6):874-8. PMID: 22306348
Leukemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) are neurally active cytokines, or neurokines. LIF signals through a receptor consisting of gp130 and the low affinity LIF receptor (LIFR),...
9.
Reiner C, Nathanson N
Handb Exp Pharmacol . 2012 Jan; (208):61-78. PMID: 22222695
Knowledge of the mechanisms responsible for the trafficking of neurotransmitter receptors away from the cell surface is of obvious importance in understanding what regulates their expression and function. This chapter...
10.
Reiner C, McCullar J, Kow R, Le J, Goodlett D, Nathanson N
PLoS One . 2010 Oct; 5(10):e13517. PMID: 20976005
Receptor internalization from the cell surface occurs through several mechanisms. Some of these mechanisms, such as clathrin coated pits, are well understood. The M(2) muscarinic acetylcholine receptor undergoes internalization via...