Neil D Ritchie
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Explore the profile of Neil D Ritchie including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
538
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Recent Articles
1.
Biddle M, Kennedy I, Kennedy J, Wright P, Ritchie N, Meek R, et al.
Bone Jt Open
. 2021 Jul;
2(7):509-514.
PMID: 34247508
Aims: Periprosthetic hip and knee infection remains one of the most severe complications following arthroplasty, with an incidence between 0.5% to 1%. This study compares the outcomes of revision surgery...
2.
Ritchie N, Evans T
mSystems
. 2019 Aug;
4(4).
PMID: 31409659
is the dominant cause of community-acquired pneumonia worldwide. Invasion of the pleural space is common and results in increased mortality. We set out to determine the bacterial and host factors...
3.
Ritchie N, Ritchie R, Bayes H, Mitchell T, Evans T
PLoS Pathog
. 2018 May;
14(5):e1007099.
PMID: 29813133
Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection. The cytokine...
4.
Ritchie N, Ijaz U, Evans T
BMC Genomics
. 2017 Oct;
18(1):807.
PMID: 29058583
Background: The bacterial pathogen Streptococcus pneumoniae colonizes the nasopharynx prior to causing disease, necessitating successful competition with the resident microflora. Cytokines of the IL-17 family are important in host defence...
5.
Ullah I, Ritchie N, Evans T
Innate Immun
. 2017 Apr;
23(5):413-423.
PMID: 28399692
Neutrophils play an important role in the innate immune response to infection with Streptococcus pneumoniae, the pneumococcus. Pneumococci are phagocytosed by neutrophils and undergo killing after ingestion. Other cellular processes...
6.
Bayes H, Ritchie N, Evans T
Infect Immun
. 2016 Oct;
84(12):3507-3516.
PMID: 27698020
Chronic pulmonary infection with Pseudomonas aeruginosa is a feature of cystic fibrosis (CF) and other chronic lung diseases. Cytokines of the interleukin-17 (IL-17) family have been proposed as important in...
7.
McCaughey L, Ritchie N, Douce G, Evans T, Walker D
Sci Rep
. 2016 Jul;
6:30201.
PMID: 27444885
Protein antibiotics, known as bacteriocins, are widely produced by bacteria for intraspecies competition. The potency and targeted action of bacteriocins suggests that they could be developed into clinically useful antibiotics...
8.
Bayes H, Ritchie N, Ward C, Corris P, Brodlie M, Evans T
J Cyst Fibros
. 2016 Jul;
15(6):759-768.
PMID: 27375092
Background: Interleukin (IL)-22 is a critical mediator of mucosal immunity and tissue regeneration, protecting against a number of respiratory pathogens. Whether IL-22 confers protection against chronic Pseudomonas aeruginosa (PA) infection...
9.
Jacobs M, Rodger A, Bell D, Bhagani S, Cropley I, Filipe A, et al.
Lancet
. 2016 May;
388(10043):498-503.
PMID: 27209148
Background: There are thousands of survivors of the 2014 Ebola outbreak in west Africa. Ebola virus can persist in survivors for months in immune-privileged sites; however, viral relapse causing life-threatening...
10.
Jabir M, Hopkins L, Ritchie N, Ullah I, Bayes H, Li D, et al.
Autophagy
. 2015 Feb;
11(1):166-82.
PMID: 25700738
The nucleotide-binding domain, leucine-rich repeat containing family caspase recruitment domain containing 4 (NLRC4) inflammasome can be activated by pathogenic bacteria via products translocated through the microbial type III secretion apparatus...