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Needhi Bhalla

Explore the profile of Needhi Bhalla including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 1158
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Recent Articles
1.
Patel B, Grobler M, Herrera A, Logari E, Ortiz V, Bhalla N
Elife . 2025 Feb; 13. PMID: 39964851
Meiotic crossover recombination is essential for both accurate chromosome segregation and the generation of new haplotypes for natural selection to act upon. This requirement is known as crossover assurance and...
2.
Patel B, Grobler M, Herrera A, Logari E, Ortiz V, Bhalla N
bioRxiv . 2024 Aug; PMID: 39185160
Meiotic crossover recombination is essential for both accurate chromosome segregation and the generation of new haplotypes for natural selection to act upon. This requirement is known as crossover assurance and...
3.
Strome S, Bhalla N, Kamakaka R, Sharma U, Sullivan W
Genetics . 2024 May; 227(3). PMID: 38805696
Gregor Mendel developed the principles of segregation and independent assortment in the mid-1800s based on his detailed analysis of several traits in pea plants. Those principles, now called Mendel's laws,...
4.
Applewhite D, Bhalla N, Cabezas-Wallscheid N, Erez N, Li M, Polo J, et al.
Nat Cell Biol . 2024 Jan; 26(1):15-18. PMID: 38228826
No abstract available.
5.
Patel B, Grobler M, Bhalla N
MicroPubl Biol . 2023 Jul; 2023. PMID: 37408786
Meiotic crossovers promote accurate chromosome segregation during gametogenesis. In , a highly conserved AAA ATPase, PCH-2, ensures that homologous chromosomes have at least one crossover, preventing meiotic defects. PCH-2 localizes...
6.
Russo A, Giacopazzi S, Deshong A, Menon M, Ortiz V, Ego K, et al.
PLoS Genet . 2023 Apr; 19(4):e1010708. PMID: 37058535
During meiotic prophase, the essential events of homolog pairing, synapsis, and recombination are coordinated with meiotic progression to promote fidelity and prevent aneuploidy. The conserved AAA+ ATPase PCH-2 coordinates these...
7.
Bhalla N
Curr Top Dev Biol . 2023 Jan; 151:317-344. PMID: 36681475
Sexual reproduction and the specialized cell division it relies upon, meiosis, are biological processes that present an incredible degree of both evolutionary conservation and divergence. One clear example of this...
8.
Bhalla N
Mol Biol Cell . 2022 Nov; 33(14):ae6. PMID: 36399618
I am extraordinarily grateful and humbled to win the ASCB Prize for Excellence in Inclusivity. However, even as I continue to center equity in all aspects of my work as...
9.
Devigne A, Bhalla N
PLoS Genet . 2021 Nov; 17(11):e1009598. PMID: 34762652
Meiotic homolog synapsis is essential to ensure accurate segregation of chromosomes during meiosis. In C. elegans, proper regulation of synapsis and a checkpoint that monitors synapsis relies on the spindle...
10.
Russo A, Nelson C, Bhalla N
MicroPubl Biol . 2021 Jan; 2021. PMID: 33490887
Meiotic chromosome segregation depends on crossover recombination to link homologous chromosomes together and promote accurate segregation in the first meiotic division. In , a conserved RING finger protein, ZHP-3, is...