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Nazi Song

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Articles 13
Citations 98
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Recent Articles
1.
Shi Z, Liu X, Wu S, Song N, Tang Q, Li H, et al.
J Med Chem . 2024 Jul; 67(14):12085-12098. PMID: 38991128
Liver fibrosis is a condition characterized by aberrant proliferation of connective tissue in the liver resulting from diverse etiological factors. G protein-coupled receptor GPR55 has recently been identified as a...
2.
Wang Y, Xue F, Cheng W, Zhao Q, Song N, Shi Z, et al.
J Med Chem . 2024 Apr; 67(8):6624-6637. PMID: 38588467
The increased remodeling of the extracellular matrix (ECM) in pulmonary fibrosis (PF) generates bioactive ECM fragments called matricryptins, which include elastin-derived peptides (EDPs). The interaction between EDPs and their receptors,...
3.
Zhao Q, Dong J, Liu H, Chen H, Yu H, Ye S, et al.
Acta Pharm Sin B . 2024 Mar; 14(3):1283-1301. PMID: 38486997
The role of co-agonists of glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR) in chronic kidney disease (CKD) remains unclear. Herein we found that GLP-1R and GCGR expression levels were...
4.
Song N, Li H, Tang Q, Luo S, Shi Z, Zhao Q, et al.
J Med Chem . 2023 Mar; 66(7):4689-4702. PMID: 36938613
Liver fibrosis is the undesirable result of excessive deposition of the extracellular matrix (ECM), and elastin is known as one of the key ECM components. Under specific pathological conditions, elastin...
5.
Song N, Xu H, Wu S, Luo S, Xu J, Zhao Q, et al.
Acta Pharm Sin B . 2023 Mar; 13(2):542-558. PMID: 36873175
Nonalcoholic fatty liver disease (NAFLD), especially nonalcoholic steatohepatitis (NASH), is a common hepatic manifestation of metabolic syndrome. However, there are no effective therapy to treat this devastating disease. Accumulating evidence...
6.
Song N, Xu H, Liu J, Zhao Q, Chen H, Yan Z, et al.
Acta Pharm Sin B . 2022 Jun; 12(5):2443-2461. PMID: 35646543
Currently, there is still no effective curative treatment for the development of late-stage liver fibrosis. Here, we have illustrated that TB001, a dual glucagon-like peptide-1 receptor/glucagon receptor (GLP-1R/GCGR) agonist with...
7.
Xu H, Gan L, Han Y, Da Y, Xiong J, Hong S, et al.
RSC Adv . 2022 May; 9(4):1909-1917. PMID: 35516120
Antibody-drug conjugates (ADCs) have recently received enormous attention as an attractive approach for cancer therapy. Although ADC design has been believed to be important for the relative efficacy of ADCs,...
8.
Chen S, Zhou X, Yang X, Li W, Li S, Hu Z, et al.
Biomolecules . 2021 Sep; 11(9). PMID: 34572586
Metformin is a widely used antidiabetic drug for cancer prevention and treatment. However, the overproduction of lactic acid and its inefficiency in cancer therapy limit its application. Here, we demonstrate...
9.
Xu H, Zhao Q, Song N, Yan Z, Lin R, Wu S, et al.
Nat Commun . 2021 Mar; 12(1):2036. PMID: 33772021
No abstract available.
10.
Yan Z, Wang D, An C, Xu H, Zhao Q, Shi Y, et al.
Acta Pharm Sin B . 2021 Feb; 11(1):100-111. PMID: 33532183
The antimicrobial peptide APKGVQGPNG (named YD), a natural peptide originating from CBSYD1, exhibited excellent antibacterial and antioxidant properties . These characteristics are closely related to inflammatory responses which is the...