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Nayan Ghosh

Explore the profile of Nayan Ghosh including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 34
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Recent Articles
1.
Verma A, Kant R, Ghosh N
Org Lett . 2024 Aug; 26(32):6814-6818. PMID: 39101709
5,10-Dihydroindeno[1,2-]indole has served as an important starting precursor for BARAC-fluor reagent in medicinal chemistry. Herein, an unprecedented -TsOH assisted intramolecular C2-arylation of NH-indoles via C(sp)-CN/C(sp)-H coupling, offering a series of...
2.
Choudhary S, Gayyur , Mandal A, Patra A, Kant R, Ghosh N
J Org Chem . 2024 Apr; 89(9):6274-6280. PMID: 38642061
Herein, a one-pot desulfonylative protocol enabled by copper(II)/zinc(II) salts to access pyrrolo[2,3-]quinolines in good to excellent yields from 2-carbonylanilines and ynamide-derived buta-1,3-diynes has been reported. Significantly, various 2-carbonylanilines carrying reactive...
3.
Gayyur , Choudhary S, Kant R, Ghosh N
Org Lett . 2023 Oct; 25(40):7400-7405. PMID: 37787541
A straightforward and atom-economical one-pot protocol catalyzed by gold(I) and zinc(II) for the synthesis of amine-substituted diaryl[,][1,6]naphthyridines from two different aromatic nitriles has been showcased. This dual-catalytic strategy is highly...
4.
Rathore M, Das N, Ghosh N, Guha R
Vet Res Commun . 2023 Jul; 48(1):1-10. PMID: 37493940
Growth hormone and insulin like growth factor-1 plays an important role in the regulation of body composition and metabolism. Growth Hormone is released from the pituitary through a specific G-protein...
5.
Choudhary S, Gayyur , Kant R, Ghosh N
J Org Chem . 2023 Jul; 88(15):10555-10564. PMID: 37466147
Herein, we present a Zn(II)-catalyzed (3 + 3) heteroannulation reaction between aromatic amines and 1,3-diynamides for the synthesis of amidoquinolines. A large number of aromatic amines are well tolerated, furnishing...
6.
Gayyur , Choudhary S, Kant R, Ghosh N
Org Lett . 2023 Jun; 25(23):4270-4275. PMID: 37272676
Herein, a catalytic synthetic transformation offering a series of -NH group-bearing aminoisoquinolines with moderate to good yields has been showcased. Interestingly, the nitrogen atom of the isoquinoline ring is coming...
7.
Saxena A, Ghosh N
J Org Chem . 2022 Dec; 88(1):300-309. PMID: 36571574
Cascade or domino reactions serve as a powerful technique for the synthesis of complex organic scaffolds in one pot. Herein, a Cu(II)-catalyzed and silica gel-assisted multicomponent reaction (MCR) between bromoalkyne-tethered...
8.
Choudhary S, Gayyur , Ghosh N
Org Biomol Chem . 2022 Aug; 20(35):7017-7021. PMID: 36001012
A one-pot copper-catalyzed [4 + 1] annulation reaction of primary amines with ynamide-derived buta-1,3-diynes for the synthesis of 2,5-diamido bearing -aryl/alkyl pyrroles in up to excellent yields has been showcased....
9.
Gayyur , Choudhary S, Kant R, Ghosh N
Chem Commun (Camb) . 2022 Jan; 58(12):1974-1977. PMID: 35044384
Scaffolds having a 1-pyrrolo[3,2-]pyridine core show significant biological activity. Herein, we report a synergetic copper/zinc-catalyzed one-step annulation reaction of 2-amino (hetero)arylnitriles with ynamide-derived buta-1,3-diynes to deliver 1-pyrrolo[3,2-]quinoline-2,4-diamine derivatives in moderate...
10.
Ramachandran R, Bhosale V, Reddy H, Atam V, Faridi M, Fatima J, et al.
Int J Infect Dis . 2021 Nov; 115:62-69. PMID: 34801738
Objective: To test efficacy, safety and tolerability of Umifenovir in non-severe COVID-19 adult patients. Methods: We carried out randomized, double-blind, placebo-controlled, multicenter, phase III trials involving adult (18-75 years), non-severe...