Nayan D Bhattacharyya
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Explore the profile of Nayan D Bhattacharyya including associated specialties, affiliations and a list of published articles.
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9
Citations
144
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Recent Articles
1.
Guo D, Jurek R, Beaumont K, Sharp D, Tan S, Mariana A, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(47):e2303978120.
PMID: 37963252
Robust high-throughput assays are crucial for the effective functioning of a drug discovery pipeline. Herein, we report the development of Invasion-Block, an automated high-content screening platform for measuring invadopodia-mediated matrix...
2.
Daniel L, Counoupas C, Bhattacharyya N, Triccas J, Britton W, Feng C
PLoS Pathog
. 2023 Jul;
19(7):e1011460.
PMID: 37405965
Recruiting large numbers of naïve lymphocytes to lymph nodes is critical for mounting an effective adaptive immune response. While most naïve lymphocytes utilize homing molecule L-selectin to enter lymph nodes,...
3.
Cootes T, Bhattacharyya N, Huang S, Daniel L, Bell-Anderson K, Stifter S, et al.
Cell Rep
. 2022 Nov;
41(7):111638.
PMID: 36384123
Modulation of individual macronutrients or caloric density is known to regulate host resistance to infection in mice. However, the impact of diet composition, independent of macronutrient and energy content, on...
4.
Daniel L, Bhattacharyya N, Counoupas C, Cai Y, Chen X, Triccas J, et al.
J Clin Invest
. 2022 Nov;
132(21).
PMID: 36317628
An effective adaptive immune response depends on the organized architecture of secondary lymphoid organs, including the lymph nodes (LNs). While the cellular composition and microanatomy of LNs under steady state...
5.
Counoupas C, Pino P, Stella A, Ashley C, Lukeman H, Bhattacharyya N, et al.
Microbiol Spectr
. 2022 Feb;
10(1):e0169521.
PMID: 35171046
Global control of COVID-19 will require the deployment of vaccines capable of inducing long-term protective immunity against SARS-CoV-2 variants. In this report, we describe an adjuvanted subunit candidate vaccine that...
6.
Counoupas C, Johansen M, Stella A, Nguyen D, Ferguson A, Aggarwal A, et al.
NPJ Vaccines
. 2021 Dec;
6(1):143.
PMID: 34848711
Global control of COVID-19 requires broadly accessible vaccines that are effective against SARS-CoV-2 variants. In this report, we exploit the immunostimulatory properties of bacille Calmette-Guérin (BCG), the existing tuberculosis vaccine,...
7.
Bhattacharyya N, Counoupas C, Daniel L, Zhang G, Cook S, Cootes T, et al.
J Immunol
. 2021 May;
206(12):2875-2887.
PMID: 34049970
The quality of T cell responses depends on the lymphocytes' ability to undergo clonal expansion, acquire effector functions, and traffic to the site of infection. Although TCR signal strength is...
8.
Counoupas C, Ferrell K, Ashhurst A, Bhattacharyya N, Nagalingam G, Stewart E, et al.
NPJ Vaccines
. 2020 Dec;
5(1):105.
PMID: 33298977
The development of effective vaccines against bacterial lung infections requires the induction of protective, pathogen-specific immune responses without deleterious inflammation within the pulmonary environment. Here, we made use of a...
9.
Bhattacharyya N, Feng C
Front Immunol
. 2020 Jun;
11:624.
PMID: 32508803
T cells are critical in orchestrating protective immune responses to cancer and an array of pathogens. The interaction between a peptide MHC (pMHC) complex on antigen presenting cells (APCs) and...