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Navnit K Prajapati

Explore the profile of Navnit K Prajapati including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 23
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Recent Articles
1.
Patel K, Patel D, Patel N, Kanhed A, Teli D, Gandhi B, et al.
J Biomol Struct Dyn . 2021 Jul; 40(20):10278-10299. PMID: 34215173
With the aim to combat a multi-faceted neurodegenerative Alzheimer's disease (AD), a series of carbazole-based semicarbazide and hydrazide derivatives were designed, synthesized and assessed for their cholinesterase (ChE) inhibitory, antioxidant...
2.
Kanhed A, Patel D, Patel N, Sinha A, Thakor P, Patel K, et al.
J Biomol Struct Dyn . 2020 Oct; 40(6):2498-2515. PMID: 33111617
To confront a disease like Alzheimer's disease having complex pathogenesis, development of multitarget-directed ligands has emerged as a promising drug discovery approach. In our endeavor towards the development of multitarget-directed...
3.
Patel D, Patel N, Kanhed A, Teli D, Patel K, Gandhi P, et al.
ACS Chem Neurosci . 2020 Oct; 11(21):3557-3574. PMID: 33073564
The inadequate clinical efficacy of the present anti-Alzheimer's disease (AD) drugs and their low impact on the progression of Alzheimer's disease in patients have revised the research focus from single...
4.
Patel D, Patel N, Kanhed A, Teli D, Patel K, Joshi P, et al.
Bioorg Chem . 2020 Jun; 101:103977. PMID: 32485470
Molecules capable of engaging with multiple targets associated with pathological condition of Alzheimer's disease have proved to be potential anti-Alzheimer's agents. In our goal to develop multitarget-directed ligands for the...
5.
Patel D, Patel N, Kanhed A, Patel S, Sinha A, Kansara D, et al.
ACS Chem Neurosci . 2019 Jul; 10(8):3635-3661. PMID: 31310717
The multifaceted nature of Alzheimer's disease (AD) demands treatment with multitarget-directed ligands (MTDLs) to confront the key pathological aberrations. A novel series of triazinoindole derivatives were designed and synthesized. In...