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Naveen Parmar

Explore the profile of Naveen Parmar including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 227
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Recent Articles
1.
Diez-Sanchez A, Lindholm H, Vornewald P, Ostrop J, Yao R, Single A, et al.
Nat Commun . 2024 Apr; 15(1):3412. PMID: 38649356
Postnatal development of the gastrointestinal tract involves the establishment of the commensal microbiota, the acquisition of immune tolerance via a balanced immune cell composition, and maturation of the intestinal epithelium....
2.
Vornewald P, Forman R, Yao R, Parmar N, Lindholm H, Lee L, et al.
Front Immunol . 2023 Oct; 14:1243528. PMID: 37869014
Intestinal epithelial homeostasis is maintained by intrinsic and extrinsic signals. The extrinsic signals include those provided by mesenchymal cell populations that surround intestinal crypts and is further facilitated by the...
3.
Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin K, Parmar N, et al.
Adv Sci (Weinh) . 2023 Jul; 10(25):e2300401. PMID: 37424036
Dermatitis herpetiformis (DH) is an inflammatory skin disorder often considered as an extra intestinal manifestation of celiac disease (CeD). Hallmarks of CeD and DH are auto-antibodies to transglutaminase 2 (TG2)...
4.
Lindholm H, Parmar N, Drurey C, Campillo Poveda M, Vornewald P, Ostrop J, et al.
Sci Immunol . 2022 May; 7(71):eabl6543. PMID: 35559665
The intestinal tract is a common site for various types of infections including viruses, bacteria, and helminths, each requiring specific modes of immune defense. The intestinal epithelium has a pivotal...
5.
Mishra S, Parmar N, Chandrakar P, Sharma C, Parveen S, Vats R, et al.
Eur J Med Chem . 2021 May; 221:113516. PMID: 33992928
The current therapeutic regimen for visceral leishmaniasis is inadequate and unsatisfactory due to toxic side effects, high cost and emergence of drug resistance. Alternative, safe and affordable antileishmanials are, therefore,...
6.
Parmar N, Burrows K, Vornewald P, Lindholm H, Zwiggelaar R, Diez-Sanchez A, et al.
PLoS Pathog . 2021 Mar; 17(3):e1009476. PMID: 33788902
Infectious and inflammatory diseases in the intestine remain a serious threat for patients world-wide. Reprogramming of the intestinal epithelium towards a protective effector state is important to manage inflammation and...
7.
Roberts L, Schnoeller C, Berkachy R, Darby M, Pillaye J, Oudhoff M, et al.
Sci Immunol . 2021 Mar; 6(57). PMID: 33674321
Innate lymphoid cells (ILCs) are critical mediators of immunological and physiological responses at mucosal barrier sites. Whereas neurotransmitters can stimulate ILCs, the synthesis of small-molecule neurotransmitters by these cells has...
8.
Chandrakar P, Seth A, Rani A, Dutta M, Parmar N, Descoteaux A, et al.
J Cell Sci . 2021 Feb; 134(5). PMID: 33589499
Notch signaling governs crucial aspects of intercellular communication spanning antigen-presenting cells and T-cells. In this study, we investigate how takes advantage of this pathway to quell host immune responses. We...
9.
Ostrop J, Zwiggelaar R, Pedersen M, Gerbe F, Bosl K, Lindholm H, et al.
Front Cell Dev Biol . 2021 Feb; 8:618552. PMID: 33575256
Intestinal organoids are an excellent model to study epithelial biology. Yet, the selection of analytical tools to accurately quantify heterogeneous organoid cultures remains limited. Here, we developed a semi-automated organoid...
10.
Zwiggelaar R, Lindholm H, Fosslie M, Pedersen M, Ohta Y, Diez-Sanchez A, et al.
Sci Adv . 2020 Sep; 6(37). PMID: 32917713
Intestinal epithelial homeostasis is maintained by adult intestinal stem cells, which, alongside Paneth cells, appear after birth in the neonatal period. We aimed to identify regulators of neonatal intestinal epithelial...