Naveen K Rajasagi
Overview
Explore the profile of Naveen K Rajasagi including associated specialties, affiliations and a list of published articles.
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21
Citations
729
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Recent Articles
1.
Rajasagi N, Rouse B
Front Immunol
. 2019 Apr;
10:512.
PMID: 30941142
The blinding inflammatory lesion stromal keratitis (SK), which occurs in some patients in response to ocular herpes simplex virus (HSV) infection, represents mainly an immune cell mediated inflammatory response to...
2.
Varanasi S, Rajasagi N, Jaggi U, Rouse B
Mucosal Immunol
. 2018 Aug;
11(6):1705-1715.
PMID: 30087443
This report deals with the possible mechanism by which IL-18 can contribute to the control and resolution of inflammatory lesions in the cornea caused by herpes simplex virus infection. Our...
3.
Rajasagi N, Rouse B
Microbes Infect
. 2018 Jan;
20(9-10):526-530.
PMID: 29329934
HSV-1 ocular infection can cause herpes stromal keratitis (SK), an immunopathological lesion. Frequent recurrences can lead to progressive corneal scaring which can result in vision impairment if left untreated. Currently,...
4.
Bhela S, Varanasi S, Jaggi U, Sloan S, Rajasagi N, Rouse B
J Immunol
. 2017 Jul;
199(4):1342-1352.
PMID: 28710254
Ocular infection with HSV causes a chronic T cell-mediated inflammatory lesion in the cornea. Lesion severity is affected by the balance of different CD4 T cell subsets, with greater severity...
5.
Rajasagi N, Bhela S, Varanasi S, Rouse B
J Leukoc Biol
. 2017 Jun;
102(5):1159-1171.
PMID: 28584076
Stromal keratitis (SK) is a chronic immunopathological lesion of the eye, caused by HSV-1 infection, and a common cause of vision impairment in humans. The inflammatory lesions in the cornea...
6.
Rajasagi N, Rouse B
Microbes Infect
. 2016 Nov;
18(12):735-746.
PMID: 27866863
CD8 T cells play an important role in controlling numerous virus infections and some tumors and therefore several strategies have been adopted to modulate CD8 T cell responses. One such...
7.
Sharma S, Rajasagi N, Veiga-Parga T, Rouse B
Microbes Infect
. 2014 Jun;
16(8):648-60.
PMID: 24956596
In many infections, especially those that are chronic such as Herpes Simplex Virus-1 (HSV-1), the outcome may be influenced by the activity of one or more types of regulatory T...
8.
Reddy P, Sehrawat S, Suryawanshi A, Rajasagi N, Khatri M, Rouse B
PLoS One
. 2014 May;
9(5):e98051.
PMID: 24846129
Long-term treatment with the fungal metabolite drug FTY720 (Fingolimod) was shown to be highly effective in controlling viral immunopathological lesions. However, in this report we show that the anti-inflammatory effect...
9.
Bhela S, Mulik S, Reddy P, Richardson R, Gimenez F, Rajasagi N, et al.
J Immunol
. 2014 Feb;
192(6):2734-43.
PMID: 24516198
HSV infection of adult humans occasionally results in life-threatening herpes simplex encephalitis (HSE) for reasons that remain to be defined. An animal system that could prove useful to model HSE...
10.
Rajasagi N, Reddy P, Mulik S, Gjorstrup P, Rouse B
Invest Ophthalmol Vis Sci
. 2013 Aug;
54(9):6269-79.
PMID: 23942967
Purpose: Neuroprotectin D1 (NPD1) is an anti-inflammatory and proresolving lipid mediator biosynthesized from the omega-3-polyunsaturated fatty acid docosahexaenoic acid (DHA). The purpose of this study is to test the therapeutic...