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Natsuko Kondo

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Articles 51
Citations 780
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Recent Articles
1.
Fujimoto T, Yamasaki O, Kanehira N, Matsushita H, Sakurai Y, Kenmotsu N, et al.
Cancer Sci . 2024 Aug; 115(10):3231-3247. PMID: 39119813
Immune checkpoint inhibitors (ICIs) are effective against many advanced malignancies. However, many patients are nonresponders to immunotherapy, and overcoming this resistance to treatment is important. Boron neutron capture therapy (BNCT)...
2.
Fujimoto T, Teraishi F, Kanehira N, Tajima T, Sakurai Y, Kondo N, et al.
Biomaterials . 2024 May; 309:122605. PMID: 38754291
Multidisciplinary therapy centered on radical surgery for resectable pancreatic cancer is expected to prolong prognosis, but relies on CA19-9 biomarker levels to determine treatment strategy. Boron neutron capture therapy (BNCT)...
3.
Kondo N, Kinouchi T, Natsumeda M, Matsuzaki J, Hirata E, Sakurai Y, et al.
J Neurooncol . 2024 Apr; 168(1):91-97. PMID: 38598087
Purpose: Boron neutron capture therapy (BNCT) is a tumor cell-selective particle-radiation therapy. In BNCT, administered p-boronophenylalanine (BPA) is selectively taken up by tumor cells, and the tumor is irradiated with...
4.
Flieger S, Takagaki M, Kondo N, Lutz Jr M, Gupta Y, Ueda H, et al.
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108137
New carborane-bearing hydroxamate matrix metalloproteinase (MMP) ligands have been synthesized for boron neutron capture therapy (BNCT) with nanomolar potency against MMP-2, -9 and -13. New analogs are based on MMP...
5.
Kondo N
Enzymes . 2022 Nov; 51:65-78. PMID: 36336409
Boron Neutron Capture Therapy (BNCT) is a tumor cell selective high LET (linear energy transfer) particle beam therapy. The patient is administrated a boron (B) compound via intravenous injection or...
6.
Kondo N, Masutani M, Imamichi S, Matsumoto Y, Nakai K
Cancer Biother Radiopharm . 2022 Sep; 38(3):173-183. PMID: 36154293
This review discusses the strategies of preclinical studies intended for accelerator-based (AB)-boron neutron capture therapy (BNCT) clinical trials, which were presented at the National Cancer Institute (NCI) Workshop on Neutron...
7.
Kondo N, Sakurai Y, Takata T, Kano K, Kume K, Maeda M, et al.
Sci Rep . 2022 May; 12(1):8718. PMID: 35610277
Brain radiation necrosis (RN) or neurocognitive disorder is a severe adverse effect that may occur after radiation therapy for malignant brain tumors or head and neck cancers. RN accompanies inflammation...
8.
Furuse M, Kawabata S, Wanibuchi M, Shiba H, Takeuchi K, Kondo N, et al.
Jpn J Clin Oncol . 2022 Jan; 52(5):433-440. PMID: 35079791
Background: Although boron neutron capture therapy has shown excellent survival data, previous studies have shown an increase in radiation necrosis against recurrent malignant glioma. Herein, we proposed that bevacizumab may...
9.
Fujimoto T, Suzuki M, Kuratsu S, Fujita I, Morishita M, Sudo T, et al.
Appl Radiat Isot . 2021 Jan; 169:109407. PMID: 33444907
Synovial sarcoma is a rare tumor requiring new treatment methods. A 46-year-old woman with primary monophasic synovial sarcoma in the left thigh involving the sciatic nerve, declining surgery because of...
10.
Michiue H, Kitamatsu M, Fukunaga A, Tsuboi N, Fujimura A, Matsushita H, et al.
J Control Release . 2020 Nov; 330:788-796. PMID: 33188824
Boron neutron capture therapy (BNCT) is a tumor selective therapy, the effectiveness of which depends on sufficient B delivery to and accumulation in tumors. In this study, we used self-assembling...