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Akihisa Takahashi

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Articles 118
Citations 1393
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Recent Articles
1.
Ma L, Li Y, Sakamoto Y, Xie L, Suzuki S, Yoshida Y, et al.
Neoplasia . 2024 Dec; 60:101099. PMID: 39674115
Background And Purpose: Although carbon-ion radiotherapy (CIRT) has led to good outcomes, controlling metastasis is still crucial for improving overall survival. This study aimed to evaluate the effectiveness of by...
2.
Zhang S, Zhang S, Wang Z, Adachi T, Yoshida Y, Takahashi A
Life Sci Space Res (Amst) . 2024 Nov; 43:54-67. PMID: 39521495
The days of returning to the Moon and landing on Mars are approaching. These long-duration missions present significant challenges, such as changes in gravity, which pose serious threats to human...
3.
Suzuki K, Tsuruoka C, Morioka T, Seo H, Ogawa M, Kambe R, et al.
Life Sci Space Res (Amst) . 2024 Apr; 41:202-209. PMID: 38670648
Explorations of the Moon and Mars are planned as future manned space missions, during which humans will be exposed to both radiation and microgravity. We do not, however, know the...
4.
Malatesta P, Kyriakidis K, Hada M, Ikeda H, Takahashi A, Saganti P, et al.
Biomolecules . 2024 Jan; 14(1). PMID: 38254688
During future space missions, astronauts will be exposed to cosmic radiation and microgravity (μG), which are known to be health risk factors. To examine the differentially expressed genes (DEG) and...
5.
Adachi T, Yoshida Y, Shibuya K, Sato K, Yamazaki Y, Kakizaki S, et al.
J Radiat Res . 2023 Jul; 64(4):693-701. PMID: 37427542
Irradiation of the liver induces a regenerative response in the nonirradiated part of the liver. It is unclear whether this leads to actual liver enlargement. The aim of this study...
6.
Hirayama J, Hattori A, Takahashi A, Furusawa Y, Tabuchi Y, Shibata M, et al.
J Pineal Res . 2022 Oct; 74(1):e12834. PMID: 36203395
Exposure to the space environment induces a number of pathophysiological outcomes in astronauts, including bone demineralization, sleep disorders, circadian clock dysregulation, cardiovascular and metabolic dysfunction, and reduced immune system function....
7.
Puspitasari A, Squarcio F, Quartieri M, Totis C, Hitrec T, Takahashi A, et al.
Sci Rep . 2022 Sep; 12(1):16405. PMID: 36180516
Hibernation or torpor is considered a possible tool to protect astronauts from the deleterious effects of space radiation that contains high-energy heavy ions. We induced synthetic torpor in rats by...
8.
Zhang S, Adachi T, Zhang S, Yoshida Y, Takahashi A
Front Cell Dev Biol . 2022 Sep; 10:965656. PMID: 36120559
The return to the Moon and the landing on Mars has emphasized the need for greater attention to the effects of partial gravity on human health. Here, we sought to...
9.
Ju Z, Thomas T, Chiu Y, Yamanouchi S, Yoshida Y, Abe J, et al.
Int J Mol Sci . 2022 Jun; 23(11). PMID: 35682810
Cultured mammalian cells have been shown to respond to microgravity (μG), but the molecular mechanism is still unknown. The study we report here is focused on molecular and cellular events...
10.
Nachankar A, Oike T, Hanaoka H, Kanai A, Sato H, Yoshida Y, et al.
Cancers (Basel) . 2021 Dec; 13(24). PMID: 34944777
Carbon ion radiotherapy is an emerging cancer treatment modality that has a greater therapeutic window than conventional photon radiotherapy. To maximize the efficacy of this extremely scarce medical resource, it...