Natsuko Kawanishi
Overview
Explore the profile of Natsuko Kawanishi including associated specialties, affiliations and a list of published articles.
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20
Citations
149
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Recent Articles
1.
Battaglin F, Baca Y, Millstein J, Yang Y, Xiu J, Arai H, et al.
J Immunother Cancer
. 2024 Jan;
12(1).
PMID: 38212126
Background: The C-C motif chemokine receptor 5 (CCR5)/C-C motif chemokine ligand 5 (CCL5) axis plays a major role in colorectal cancer (CRC). We aimed to characterize the molecular features associated...
2.
Wang J, Millstein J, Yang Y, Stintzing S, Arai H, Battaglin F, et al.
EClinicalMedicine
. 2023 Feb;
57:101827.
PMID: 36816347
Background: Antiangiogenic drug (AAD)-triggered oxygen and nutrient depletion through suppression of angiogenesis switches glucose-dependent to lipid-dependent metabolism. Blocking fatty acid oxidation can enhance AAD-mediated anti-tumor effects in colorectal cancer (CRC)....
3.
Wang J, Xiu J, Farrell A, Baca Y, Arai H, Battaglin F, et al.
Lancet Oncol
. 2023 Jan;
24(2):151-161.
PMID: 36681091
Background: Genomic signatures contributing to high tumour mutational burden (TMB-H) independent from mismatch-repair deficiency (dMMR) or microsatellite instability-high (MSI-H) status are not well studied. We aimed to characterise molecular features...
4.
Wang J, Xiao Y, Loupakis F, Stintzing S, Yang Y, Arai H, et al.
Eur J Cancer
. 2022 Jun;
172:22-30.
PMID: 35749909
Background: The activation of stimulator of interferon genes (STING) was reported to enhance cetuximab-mediated natural killer cell activation and dendritic cell maturation. Polymorphisms in genes in the cyclic GMP-AMP synthase...
5.
Arai H, Millstein J, Yang Y, Stintzing S, Wang J, Battaglin F, et al.
Clin Colorectal Cancer
. 2022 Jun;
21(3):259-266.
PMID: 35710481
Background: Reactive oxygen species activate EGFR/RAS/MAPK signaling either through the inactivation of phosphatases or by direct oxidation of kinases. We hypothesized that functional single-nucleotide polymorphisms (SNPs) in antioxidant genes link...
6.
Arai H, Elliott A, Millstein J, Xiu J, Ou F, Innocenti F, et al.
Oncogene
. 2021 Nov;
41(2):260-267.
PMID: 34728807
Loss-of-function alterations of Neurofibromin 1 (NF1) activate RAS, a driver of colorectal cancer. However, the clinical implications of NF1 alterations are largely unknown. We performed a comprehensive molecular profiling of...
7.
Arai H, Xiao Y, Millstein J, Wang J, Battaglin F, Kawanishi N, et al.
Br J Cancer
. 2021 Oct;
126(1):72-78.
PMID: 34689170
Background: The TIMELESS-TIPIN complex protects the replication fork from replication stress induced by chemotherapeutic drugs. We hypothesised genetic polymorphisms of the TIMELESS-TIPIN complex may affect the response, progression-free survival (PFS),...
8.
Wang J, Xiu J, Baca Y, Battaglin F, Arai H, Kawanishi N, et al.
Oncogene
. 2021 Jun;
40(30):4894-4905.
PMID: 34163031
Frequent mutations of genes in the histone-lysine N-methyltransferase 2 (KMT2) family members were identified in gastric cancers (GCs). Understanding how gene mutations of KMT2 family affect cancer progression and tumor...
9.
Arai H, Millstein J, Loupakis F, Stintzing S, Wang J, Battaglin F, et al.
Eur J Cancer
. 2021 Apr;
150:133-142.
PMID: 33901792
Background: Cancer stem cells (CSCs) are primarily maintained by a network of pluripotency transcription factors (PTFs). Given a close relationship of CSC regulation with epidermal growth factor receptor and vascular...
10.
Arai H, Cao S, Battaglin F, Wang J, Kawanishi N, Tokunaga R, et al.
Mol Cancer Ther
. 2021 Mar;
20(6):1153-1160.
PMID: 33785650
RNA-binding proteins (RBPs) regulate many posttranscriptional cellular activities. Accumulating evidence suggests associations between RBPs with colonic tumorigenesis and chemosensitivity. We investigated the prognostic and predictive values of SNPs of genes...