Nathaniel S Wang
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Explore the profile of Nathaniel S Wang including associated specialties, affiliations and a list of published articles.
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6
Citations
691
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Recent Articles
1.
Maine C, Miyake-Stoner S, Spasova D, Picarda G, Chou A, Brand E, et al.
Nat Commun
. 2025 Jan;
16(1):456.
PMID: 39774967
Self-replicating RNA (srRNA) technology, in comparison to mRNA vaccines, has shown dose-sparing by approximately 10-fold and more durable immune responses. However, no improvements are observed in the adverse events profile....
2.
Aliahmad P, Miyake-Stoner S, Geall A, Wang N
Cancer Gene Ther
. 2022 Feb;
30(6):785-793.
PMID: 35194198
RNA technology has recently come to the forefront of innovative medicines and is being explored for a wide range of therapies, including prophylactic and therapeutic vaccines, biotherapeutic protein expression and...
3.
Maine C, Richard G, Spasova D, Miyake-Stoner S, Sparks J, Moise L, et al.
Mol Ther
. 2020 Dec;
29(3):1186-1198.
PMID: 33278563
Historically poor clinical results of tumor vaccines have been attributed to weakly immunogenic antigen targets, limited specificity, and vaccine platforms that fail to induce high-quality polyfunctional T cells, central to...
4.
Wang N, McHeyzer-Williams L, Okitsu S, Burris T, Reiner S, McHeyzer-Williams M
Nat Immunol
. 2012 May;
13(6):604-11.
PMID: 22561605
Antibody class defines function in B cell immunity, but how class is propagated into B cell memory remains poorly understood. Here we demonstrate that memory B cell subsets unexpectedly diverged...
5.
Wang J, Friedman G, Doyon Y, Wang N, Li C, Miller J, et al.
Genome Res
. 2012 Mar;
22(7):1316-26.
PMID: 22434427
Zinc-finger nucleases (ZFNs) drive highly efficient genome editing by generating a site-specific DNA double-strand break (DSB) at a predetermined site in the genome. Subsequent repair of this break via the...
6.
Miller J, Holmes M, Wang J, Guschin D, Lee Y, Rupniewski I, et al.
Nat Biotechnol
. 2007 Jul;
25(7):778-85.
PMID: 17603475
Genome editing driven by zinc-finger nucleases (ZFNs) yields high gene-modification efficiencies (>10%) by introducing a recombinogenic double-strand break into the targeted gene. The cleavage event is induced using two custom-designed...