Nathaniel Marchetti
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Explore the profile of Nathaniel Marchetti including associated specialties, affiliations and a list of published articles.
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92
Citations
2269
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Recent Articles
1.
Lin C, Hayek H, Simborio H, Karim L, Bahmed K, Bolla S, et al.
Aging Dis
. 2025 Feb;
PMID: 39908265
Homeostatic imbalance and lung function decline are central physiological characteristics of aging and susceptibility to respiratory diseases. Senescence contributes to tissue damage and alveolar epithelial cell injury and decreases reparative...
2.
Dransfield M, Marchetti N, Kalhan R, Reyner D, Dixon A, Rheault T, et al.
Chron Respir Dis
. 2025 Jan;
22:14799731251314874.
PMID: 39854278
Background: The efficacy and safety of ensifentrine, a novel PDE3/PDE4 inhibitor, were previously evaluated in the ENHANCE-1 (NCT04535986) and ENHANCE-2 (NCT04542057) trials. Here, we present a pooled post-hoc subgroup analysis...
3.
Simborio H, Hayek H, Kosmider B, Elrod J, Bolla S, Marchetti N, et al.
Cell Commun Signal
. 2024 Nov;
22(1):562.
PMID: 39578839
Background: Alveolar type II (ATII) cells have a stem cell potential in the adult lung and repair the epithelium after injury induced by harmful factors. Their damage contributes to emphysema...
4.
Gangemi A, Dass C, Zhao H, Patel M, Marchetti N, Criner G, et al.
Respir Med
. 2024 Nov;
235:107860.
PMID: 39557207
Purpose: Point of Care Ultrasound (POCUS) is widely used to evaluate pleural apposition in acute disease; however, the prevalence of abnormal findings among emphysematous patients is unknown. The aim of...
5.
Puthusseri B, Bhagavath A, Korir D, Shetty R, Johnson G, Stankowska D, et al.
Am J Respir Cell Mol Biol
. 2024 Sep;
PMID: 39269467
Impaired alveolar epithelial regeneration in patients with idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) is attributed to telomere dysfunction in type II alveolar epithelial cells (ACs). Genetic...
6.
Curtis J, Bateman L, Murray S, Couper D, Labaki W, Freeman C, et al.
Chronic Obstr Pulm Dis
. 2024 Aug;
11(5):444-459.
PMID: 39159077
Background: The biological mechanisms leading some tobacco-exposed individuals to develop early-stage chronic obstructive pulmonary disease (COPD) are poorly understood. This knowledge gap hampers development of disease-modifying agents for this prevalent...
7.
Yang Q, Langston J, Prosniak R, Pettigrew S, Zhao H, Perez E, et al.
Front Immunol
. 2024 Mar;
15:1341752.
PMID: 38524125
Purpose: Sepsis is a clinical syndrome defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis is a highly heterogeneous syndrome with distinct phenotypes that impact...
8.
McCluskey E, Liu N, Pandey A, Marchetti N, Kelsen S, Sajjan U
Respir Res
. 2024 Mar;
25(1):120.
PMID: 38468259
Background: Airway basal cells (BC) from patients with chronic obstructive pulmonary disease (COPD) regenerate abnormal airway epithelium and this was associated with reduced expression of several genes involved in epithelial...
9.
Sciurba F, Dransfield M, Kim V, Marchetti N, Comellas A, Hogarth D, et al.
BMJ Open Respir Res
. 2023 Dec;
10(1).
PMID: 38151258
Introduction: Chronic bronchitis (CB), a phenotype of chronic obstructive pulmonary disease (COPD) characterised by persistent cough and mucus hypersecretion, is associated with poor outcomes despite guideline-based treatment. Bronchial rheoplasty (BR)...
10.
Hayek H, Rehbini O, Kosmider B, Brandt T, Chatila W, Marchetti N, et al.
Am J Respir Cell Mol Biol
. 2023 Dec;
70(4):259-282.
PMID: 38117249
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease caused by an aberrant repair of injured alveolar epithelial cells. The maintenance of the alveolar epithelium and its regeneration after...