Nathaniel D Anderson
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Explore the profile of Nathaniel D Anderson including associated specialties, affiliations and a list of published articles.
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20
Citations
355
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Recent Articles
1.
Treger T, Wegert J, Wenger A, Coorens T, Al-Saadi R, Kemps P, et al.
Cancer Discov
. 2024 Dec;
15(2):286-298.
PMID: 39665570
Approximately 10% of children with cancer harbor a mutation in a predisposition gene. In children with the kidney cancer Wilms tumor, the prevalence is as high as 30%. Certain predispositions...
2.
Lawrence J, Roberts K, Tuck E, Li T, Mamanova L, Balogh P, et al.
Nat Commun
. 2024 Nov;
15(1):10023.
PMID: 39567486
Positional coding along the anterior-posterior axis is regulated by HOX genes, whose 3' to 5' expression correlates with location along this axis. The precise utilisation of HOX genes in different...
3.
Treger T, Lawrence J, Anderson N, Coorens T, Letunovska A, Abby E, et al.
Nat Commun
. 2023 Sep;
14(1):5826.
PMID: 37749094
Reninomas are exceedingly rare renin-secreting kidney tumours that derive from juxtaglomerular cells, specialised smooth muscle cells that reside at the vascular inlet of glomeruli. They are the central component of...
4.
Anderson N, Birch J, Accogli T, Criado I, Khabirova E, Parks C, et al.
Nat Med
. 2023 Jul;
29(7):1700-1709.
PMID: 37407840
In the context of relapsed and refractory childhood pre-B cell acute lymphoblastic leukemia (R/R B-ALL), CD19-targeting chimeric antigen receptor (CAR)-T cells often induce durable remissions, which requires the persistence of...
5.
Anderson N, Behjati S
Immunity
. 2023 Jan;
56(1):11-13.
PMID: 36630910
In a study recently in Nature, Galeano Niño et al. use spatial profiling and single-cell RNA sequencing to delineate the spatial organization of microbiota in cancer. Their findings demonstrate that...
6.
Light N, Layeghifard M, Attery A, Subasri V, Zatzman M, Anderson N, et al.
Nat Commun
. 2023 Jan;
14(1):77.
PMID: 36604421
Li-Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome associated with germline TP53 pathogenic variants. Here, we perform whole-genome sequence (WGS) analysis of tumors from 22 patients with TP53 germline...
7.
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations
Villani A, Davidson S, Kanwar N, Lo W, Li Y, Cohen-Gogo S, et al.
Nat Cancer
. 2022 Dec;
4(2):203-221.
PMID: 36585449
We conducted integrative somatic-germline analyses by deeply sequencing 864 cancer-associated genes, complete genomes and transcriptomes for 300 mostly previously treated children and adolescents/young adults with cancer of poor prognosis or...
8.
Trinh M, Pacyna C, Kildisiute G, Thevanesan C, Piapi A, Ambridge K, et al.
Commun Biol
. 2022 Sep;
5(1):884.
PMID: 36071103
A fundamental step of tumour single cell mRNA analysis is separating cancer and non-cancer cells. We show that the common approach to separation, using shifts in average expression, can lead...
9.
Stosic A, Fuligni F, Anderson N, Davidson S, De Borja R, Acker M, et al.
Cancer Res
. 2021 Sep;
81(22):5625-5637.
PMID: 34535459
Pediatric papillary thyroid carcinoma (PPTC) is clinically distinct from adult-onset disease. Although there are higher rates of metastasis and recurrence in PPTC, prognosis remains highly favorable. Molecular characterization of PPTC...
10.
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival
Anderson N, Babichev Y, Fuligni F, Comitani F, Layeghifard M, Venier R, et al.
Nat Commun
. 2021 Jul;
12(1):4496.
PMID: 34301934
Leiomyosarcomas (LMS) are genetically heterogeneous tumors differentiating along smooth muscle lines. Currently, LMS treatment is not informed by molecular subtyping and is associated with highly variable survival. While disease site...