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Nathan D Grubaugh

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Articles 178
Citations 10975
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Recent Articles
1.
Johnson R, Breban M, Nolan B, Sodeinde A, Ott I, Ross P, et al.
bioRxiv . 2025 Feb; PMID: 39975058
Dengue virus (DENV) is a mosquito-borne virus that poses a continued and increasing threat to public health. A promising strategy to mitigate the burden of DENV is introgression of the...
2.
Kalinich C, Gonzalez F, Osmaston A, Breban M, Distefano I, Leon C, et al.
bioRxiv . 2025 Jan; PMID: 39763738
Pathogen sequencing is an important tool for disease surveillance and demonstrated its high value during the COVID-19 pandemic. Viral sequencing during the pandemic allowed us to track disease spread, quickly...
3.
Klontz E, Chowdhury N, Holbrook N, Solomon I, Telford 3rd S, Aliota M, et al.
Viruses . 2024 Nov; 16(11). PMID: 39599768
Powassan virus (POWV) is an emerging tick-borne virus that causes severe meningoencephalitis in the United States, Canada, and Russia. Serology is generally the preferred diagnostic modality, but PCR on cerebrospinal...
4.
Grubaugh N, Torres-Hernandez D, Murillo-Ortiz M, Davalos D, Lopez P, Hurtado I, et al.
Emerg Infect Dis . 2024 Oct; 30(11):2391-2395. PMID: 39378873
Dengue cases rose to record levels during 2023-2024. We investigated dengue in Valle del Cauca, Colombia, to determine if specific virus serotypes or lineages caused its large outbreak. We detected...
5.
Li K, Chaguza C, Stamp J, Chew Y, Chen N, Ferguson D, et al.
PLoS Comput Biol . 2024 Sep; 20(9):e1012469. PMID: 39288189
Significant variations have been observed in viral copies generated during SARS-CoV-2 infections. However, the factors that impact viral copies and infection dynamics are not fully understood, and may be inherently...
6.
Hill V, Cleemput S, Pereira J, Gifford R, Fonseca V, Tegally H, et al.
PLoS Biol . 2024 Sep; 22(9):e3002834. PMID: 39283942
Dengue virus (DENV) is currently causing epidemics of unprecedented scope in endemic settings and expanding to new geographical areas. It is therefore critical to track this virus using genomic surveillance....
7.
Miguel I, Feliz E, Agramonte R, Martinez P, Vergara C, Imbert Y, et al.
BMC Infect Dis . 2024 Jul; 24(1):751. PMID: 39075335
Background: Dengue fever remains a significant public health challenge in tropical and subtropical regions, with its transmission dynamics being influenced by both environmental factors and human mobility. The Dominican Republic,...
8.
Pena-Hernandez M, Alfajaro M, Filler R, Moriyama M, Keeler E, Ranglin Z, et al.
Nat Microbiol . 2024 Jul; 9(8):2038-2050. PMID: 39075235
Circulating bat coronaviruses represent a pandemic threat. However, our understanding of bat coronavirus pathogenesis and transmission potential is limited by the lack of phenotypically characterized strains. We created molecular clones...
9.
Grubaugh N, Torres-Hernandez D, Murillo-Ortiz M, Davalos D, Lopez P, Hurtado I, et al.
medRxiv . 2024 Jul; PMID: 39072046
Global dengue cases rapidly rose to record levels in 2023-24. We investigated this trend in Valle del Cauca, Colombia to determine if specific dengue virus serotypes or lineages were responsible...
10.
Lopes R, Pham K, Klaassen F, Chitwood M, Hahn A, Redmond S, et al.
Cell Rep . 2024 Jul; 43(7):114451. PMID: 38970788
Omicron surged as a variant of concern in late 2021. Several distinct Omicron variants appeared and overtook each other. We combined variant frequencies and infection estimates from a nowcasting model...