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Nathan C Twaddle

Explore the profile of Nathan C Twaddle including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Hakkak R, Korourian S, Li W, Spray B, Twaddle N, Randolph C, et al.
Front Nutr . 2024 Nov; 11:1487859. PMID: 39529929
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major public health concern that is exacerbated by the obesity pandemic. Dietary interventions have the potential to alleviate obesity-associated MASLD through...
2.
Silva C, Kudlyk T, Tryndyak V, Twaddle N, Robinson B, Gu Q, et al.
J Appl Toxicol . 2023 Jul; 43(12):1872-1882. PMID: 37501093
Our previous study showed that sodium arsenite (200 mg/L) affected the nervous system and induced motor neuron development via the Sonic hedgehog pathway in zebrafish larvae. To gain more insight...
3.
Li W, Twaddle N, Spray B, Nounamo B, Monzavi-Karbassi B, Hakkak R
J Med Food . 2023 Jan; 26(2):120-127. PMID: 36720082
Soy's anti-inflammatory properties contribute to the health benefits of soy foods. This study was designed to investigate the bioavailability of soy isoflavones and whether the isoflavone content of soy protein...
4.
Kanungo J, Twaddle N, Silva C, Robinson B, Wolle M, Conklin S, et al.
Neurosci Lett . 2023 Jan; 795:137042. PMID: 36587726
The mechanism of inorganic arsenic-induced neurotoxicity at the cellular level is not known. In zebrafish, teratological effects of inorganic arsenic have been shown at various concentrations. Here, we used similar...
5.
Doerge D, Twaddle N, Churchwell M, Beland F
Environ Int . 2020 Sep; 144:106086. PMID: 32889486
Arsenic (As) is a common contaminant in the earth's crust and widely distributed in food and drinking water. As exposures have been associated with human disease, including cancer, diabetes, lung...
6.
Twaddle N, Beland F, Doerge D
Food Chem Toxicol . 2019 Aug; 133:110760. PMID: 31421213
Arsenic is a common toxic contaminant in food and drinking water. Metabolic activation of arsenic species produces reactive trivalent intermediates that can disrupt cellular regulatory systems by covalent binding to...
7.
Twaddle N, Vanlandingham M, Beland F, Doerge D
Food Chem Toxicol . 2019 May; 130:22-31. PMID: 31091427
Arsenic species contaminate food and water, with typical dietary intake below 1 μg/kg bw/d. Exposure to arsenic in heavily contaminated drinking water is associated with human diseases, including cardiovascular and...
8.
Pande P, Fleck S, Twaddle N, Churchwell M, Doerge D, Teeguarden J
Food Chem Toxicol . 2018 Dec; 125:341-353. PMID: 30553876
Evaluating the biological significance of human-relevant exposures to environmental estrogens involves assessing the individual and total estrogenicity of endogenous and exogenous estrogens found in serum, for example from biomonitoring studies....
9.
Twaddle N, Vanlandingham M, Beland F, Fisher J, Doerge D
Food Chem Toxicol . 2018 Oct; 123:28-41. PMID: 30342114
Arsenic is a ubiquitous contaminant, with typical human dietary intake below 1 μg/kg bw/d and extreme drinking water exposures up to ∼50 μg/kg bw/d. The formation and binding of trivalent...
10.
Twaddle N, Vanlandingham M, Fisher J, Doerge D
Food Chem Toxicol . 2018 Oct; 121:676-686. PMID: 30278242
Arsenic is a ubiquitous contaminant, with typical dietary intake below 1 μg/kg bw/d and drinking water exposures up to 50 μg/kg bw/d. Arsenic exposures are associated with human diseases and...