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Nathan C Layman

Explore the profile of Nathan C Layman including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Layman N, Basinski A, Zhang B, Eskew E, Bird B, Ghersi B, et al.
Ecol Lett . 2023 Sep; 26(11):1974-1986. PMID: 37737493
Zoonotic diseases threaten human health worldwide and are often associated with anthropogenic disturbance. Predicting how disturbance influences spillover risk is critical for effective disease intervention but difficult to achieve at...
2.
Nuismer S, Layman N, Redwood A, Chan B, Bull J
Synth Biol (Oxf) . 2021 Oct; 6(1):ysab018. PMID: 34712842
Diverse applications rely on engineering microbes to carry and express foreign transgenes. This engineered baggage rarely benefits the microbe and is thus prone to rapid evolutionary loss when the microbe...
3.
Layman N, Tuschhoff B, Nuismer S
Virus Evol . 2021 Mar; 7(1):veab002. PMID: 33680502
The danger posed by emerging infectious diseases necessitates the development of new tools that can mitigate the risk of animal pathogens spilling over into the human population. One promising approach...
4.
Layman N, Tuschhoff B, Basinski A, Remien C, Bull J, Nuismer S
Evol Appl . 2021 Mar; 14(2):348-359. PMID: 33664781
Genetically engineered organisms are prone to evolve in response to the engineering. This evolution is often undesirable and can negatively affect the purpose of the engineering. Methods that maintain the...
5.
Basinski A, Fichet-Calvet E, Sjodin A, Varrelman T, Remien C, Layman N, et al.
PLoS Comput Biol . 2021 Mar; 17(3):e1008811. PMID: 33657095
Forecasting the risk of pathogen spillover from reservoir populations of wild or domestic animals is essential for the effective deployment of interventions such as wildlife vaccination or culling. Due to...
6.
Prior C, Layman N, Koski M, Galloway L, Busch J
Mol Ecol . 2020 Sep; 29(22):4473-4486. PMID: 32978776
It is often expected that temperate plants have expanded their geographical ranges northward from primarily southern refugia. Evidence for this hypothesis is mixed in eastern North American species, and there...
7.
Koski M, Layman N, Prior C, Busch J, Galloway L
Evol Lett . 2019 Oct; 3(5):500-512. PMID: 31636942
Colonization at expanding range edges often involves few founders, reducing effective population size. This process can promote the evolution of self-fertilization, but implicating historical processes as drivers of trait evolution...
8.
Layman N, Busch J
Evolution . 2018 Aug; 72(10):2025-2037. PMID: 30136722
Inbreeding depression is dependent on the ploidy of populations and can inhibit the evolution of selfing. While polyploids should generally harbor less inbreeding depression than diploids at equilibrium, it has...
9.
Layman N, Fernando M, Herlihy C, Busch J
Evolution . 2017 Jan; 71(4):884-897. PMID: 28075480
In flowering plants, shifts from outcrossing to partial or complete self-fertilization have occurred independently thousands of times, yet the underlying adaptive processes are difficult to discern. Selfing's ability to provide...