Nathan A Yates
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Explore the profile of Nathan A Yates including associated specialties, affiliations and a list of published articles.
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49
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1435
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Recent Articles
11.
Bell-Temin H, Yousefzadeh M, Bondarenko A, Quarles E, Jones-Laughner J, Robbins P, et al.
Aging (Albany NY)
. 2019 Feb;
11(3):1045-1061.
PMID: 30745468
Aging is an ill-defined process that increases the risk of morbidity and mortality. Aging is also heterogeneous meaning that biological and chronological age can differ. Here, we used unbiased differential...
12.
Li Y, Merkel C, Zeng X, Heier J, Cantrell P, Sun M, et al.
J Cell Sci
. 2019 Jan;
132(3).
PMID: 30630894
The junctional complexes that couple cardiomyocytes must transmit the mechanical forces of contraction while maintaining adhesive homeostasis. The adherens junction (AJ) connects the actomyosin networks of neighboring cardiomyocytes and is...
13.
Krivinko J, Erickson S, Ding Y, Sun Z, Penzes P, MacDonald M, et al.
Am J Psychiatry
. 2018 Jul;
175(10):999-1009.
PMID: 30021459
Objective: The presence of psychosis in Alzheimer's disease denotes a phenotype with more rapid cognitive deterioration than in Alzheimer's disease without psychosis. Discovery of novel pharmacotherapies that engage therapeutic targets...
14.
Robinson A, Yousefzadeh M, Rozgaja T, Wang J, Li X, Tilstra J, et al.
Redox Biol
. 2018 May;
17:259-273.
PMID: 29747066
Accumulation of senescent cells over time contributes to aging and age-related diseases. However, what drives senescence in vivo is not clear. Here we used a genetic approach to determine if...
15.
Aebersold R, Agar J, Jonathan Amster I, Baker M, Bertozzi C, Boja E, et al.
Nat Chem Biol
. 2018 Feb;
14(3):206-214.
PMID: 29443976
Despite decades of accumulated knowledge about proteins and their post-translational modifications (PTMs), numerous questions remain regarding their molecular composition and biological function. One of the most fundamental queries is the...
16.
Khetarpal S, Zeng X, Millar J, Vitali C, Hanasoge Somasundara A, Zanoni P, et al.
Nat Med
. 2017 Aug;
23(9):1086-1094.
PMID: 28825717
Recent large-scale genetic sequencing efforts have identified rare coding variants in genes in the triglyceride-rich lipoprotein (TRL) clearance pathway that are protective against coronary heart disease (CHD), independently of LDL...
17.
Tan R, Nakajima S, Wang Q, Sun H, Xue J, Wu J, et al.
Mol Cell
. 2017 Feb;
65(5):818-831.e5.
PMID: 28216227
Telomeric repeat binding factor 1 (TRF1) is essential to the maintenance of telomere chromatin structure and integrity. However, how telomere integrity is maintained, especially in response to damage, remains poorly...
18.
Chen W, Wang Z, Missinato M, Park D, Long D, Liu H, et al.
Sci Adv
. 2017 Feb;
2(11):e1600844.
PMID: 28138518
Heart attack is a global health problem that leads to significant morbidity, mortality, and health care burden. Adult human hearts have very limited regenerative capability after injury. However, evolutionarily primitive...
19.
Braganza A, Li J, Zeng X, Yates N, Dey N, Andrews J, et al.
J Biol Chem
. 2016 Dec;
292(6):2470-2484.
PMID: 28003368
Recent genome-wide studies found that patients with hypotonia, developmental delay, intellectual disability, congenital anomalies, characteristic facial dysmorphic features, and low cholesterol levels suffer from aufman culocerebrofacial yndrome (KOS, also reported...
20.
Edmunds L, Otero P, Sharma L, DSouza S, Dolezal J, David S, et al.
Oncotarget
. 2016 Apr;
7(21):30379-95.
PMID: 27105497
Establishing c-Myc's (Myc) role in liver regeneration has proven difficult particularly since the traditional model of partial hepatectomy may provoke an insufficiently demanding proliferative stress. We used a model of...