Nathan A Yates
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Explore the profile of Nathan A Yates including associated specialties, affiliations and a list of published articles.
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49
Citations
1435
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Recent Articles
1.
Chen Y, Zeng X, Diaz J, Sehrawat A, Lafferty T, Boslett J, et al.
J Neurochem
. 2024 May;
168(9):2736-2750.
PMID: 38814273
The reliability of plasma biomarkers of Alzheimer's disease (AD) can be compromised by protease-induced degradation. This can limit the feasibility of conducting plasma biomarker studies in environments that lack the...
2.
Inanc B, Fang Q, Andrews J, Zeng X, Clark J, Li J, et al.
bioRxiv
. 2024 Apr;
PMID: 38645048
The multitude of DNA lesion types, and the nuclear dynamic context in which they occur, present a challenge for genome integrity maintenance as this requires the engagement of different DNA...
3.
Chen Y, Zeng X, Lee J, Sehrawat A, Lafferty T, Boslett J, et al.
medRxiv
. 2024 Mar;
PMID: 38496591
Introduction: The reliability of plasma Alzheimer's disease (AD) biomarkers can be compromised by protease-induced degradation. This limits the feasibility of conducting plasma biomarker studies in environments that lack the capacity...
4.
Cai X, Li S, Zeng X, Xu M, Wang Z, Singhi A, et al.
Cell Mol Gastroenterol Hepatol
. 2023 May;
16(3):473-495.
PMID: 37192689
Background & Aims: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer deaths in the United States. Tyrosine sulfation, catalyzed by the tyrosylprotein sulfotransferase 2 (TPST2), is a...
5.
Li J, Garavaglia S, Ye Z, Moretti A, Belyaeva O, Beiser A, et al.
Commun Biol
. 2021 Dec;
4(1):1420.
PMID: 34934174
Elevated aldehyde dehydrogenase (ALDH) activity correlates with poor outcome for many solid tumors as ALDHs may regulate cell proliferation and chemoresistance of cancer stem cells (CSCs). Accordingly, potent, and selective...
6.
Li J, Saville K, Ibrahim M, Zeng X, McClellan S, Angajala A, et al.
NAR Cancer
. 2021 Nov;
3(4):zcab044.
PMID: 34806016
Elevated expression of the DNA damage response proteins PARP1 and poly(ADP-ribose) glycohydrolase (PARG) in glioma stem cells (GSCs) suggests that glioma may be a unique target for PARG inhibitors (PARGi)....
7.
Knowlton J, Gestaut D, Ma B, Taylor G, Seven A, Leitner A, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(11).
PMID: 33836586
Intracellular protein homeostasis is maintained by a network of chaperones that function to fold proteins into their native conformation. The eukaryotic TRiC chaperonin (TCP1-ring complex, also called CCT for cytosolic...
8.
Toptan T, Cantrell P, Zeng X, Liu Y, Sun M, Yates N, et al.
JCI Insight
. 2020 Oct;
5(22).
PMID: 33055416
The challenge of discovering a completely new human tumor virus of unknown phylogeny or sequence depends on detecting viral molecules and differentiating them from host molecules in the virus-associated neoplasm....
9.
Buck T, Zeng X, Cantrell P, Cattley R, Hasanbasri Z, Yates M, et al.
Mol Cell Proteomics
. 2020 Sep;
19(11):1896-1909.
PMID: 32868373
Studies in the yeast have helped define mechanisms underlying the activity of the ubiquitin-proteasome system (UPS), uncover the proteasome assembly pathway, and link the UPS to the maintenance of cellular...
10.
Bakkenist C, Czambel R, Lin Y, Yates N, Zeng X, Shogan J, et al.
DNA Repair (Amst)
. 2019 Jun;
80:1-7.
PMID: 31176958
Since many anticancer therapies target DNA and DNA damage response pathways, biomarkers of DNA damage endpoints may prove valuable in basic and clinical cancer research. Ataxia telangiectasia-mutated (ATM) kinase is...