Nathalie Thieblemont
Overview
Explore the profile of Nathalie Thieblemont including associated specialties, affiliations and a list of published articles.
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35
Citations
1186
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Recent Articles
1.
Tlili A, Pintard C, Hurtado-Nedelec M, Liu D, Marzaioli V, Thieblemont N, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(3):e2209184120.
PMID: 36626553
Monocytes play a key role in innate immunity by eliminating pathogens, releasing high levels of cytokines, and differentiating into several cell types, including macrophages and dendritic cells. Similar to other...
2.
London J, Dumoitier N, Lofek S, Dion J, Chaigne B, Mocek J, et al.
Rheumatology (Oxford)
. 2020 Oct;
60(5):2157-2168.
PMID: 33026090
Objectives: To characterize lymphocytes dysregulation in patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). Methods: Using flow cytometry, we analysed B- and T-cell subsets in peripheral blood from...
3.
Ohayon D, De Chiara A, Dang P, Thieblemont N, Chatfield S, Marzaioli V, et al.
J Exp Med
. 2019 Nov;
216(12):2900.
PMID: 31732507
No abstract available.
4.
Ohayon D, De Chiara A, Dang P, Thieblemont N, Chatfield S, Marzaioli V, et al.
J Exp Med
. 2019 Sep;
216(11):2669-2687.
PMID: 31492810
Neutrophils produce high levels of reactive oxygen species (ROS) by NADPH oxidase that are crucial for host defense but can lead to tissue injury when produced in excess. We previously...
5.
Everts-Graber J, Martin K, Thieblemont N, Mocek J, Roccabianca A, Chafey P, et al.
Kidney Int
. 2019 May;
96(2):397-408.
PMID: 31142442
Granulomatosis with polyangiitis (GPA) is an autoimmune vasculitis associated with anti-neutrophil-cytoplasmic antibodies (ANCA) against proteinase 3 leading to kidney damage. Neutrophils from those patients have increased expression of membrane proteinase...
6.
Chatfield S, Thieblemont N, Witko-Sarsat V
J Innate Immun
. 2018 Sep;
10(5-6):422-431.
PMID: 30257246
Research into neutrophil biology in the last 10 years has uncovered a number of unexpected aspects of this still mysterious innate immune cell. Advances in technology have allowed visualisation of...
7.
Thieblemont N, Witko-Sarsat V, Ariel A
Eur J Clin Invest
. 2018 Jul;
48 Suppl 2:e12990.
PMID: 30039869
Neutrophils are critically involved in host defence and they also modulate the inflammatory process. Turning the inflammatory response towards a resolutive outcome requires a dialogue between apoptotic neutrophils and proresolving...
8.
Tacnet-Delorme P, Gabillet J, Chatfield S, Thieblemont N, Frachet P, Witko-Sarsat V
Front Immunol
. 2018 May;
9:818.
PMID: 29755460
Proteinase 3 (PR3) is the autoantigen in granulomatosis with polyangiitis, an autoimmune necrotizing vasculitis associated with anti-neutrophil cytoplasmic antibodies (ANCAs). Moreover, PR3 is a serine protease whose membrane expression can...
9.
Martin K, Pederzoli-Ribeil M, Pacreau E, Burgener S, Dahdah A, Candalh C, et al.
J Immunol
. 2017 Oct;
199(11):3914-3924.
PMID: 29079698
Proteinase 3 (PR3) is a myeloid serine protease expressed in neutrophils, monocytes, and macrophages. PR3 has a number of well-characterized proinflammatory functions, including cleaving and activating chemokines and controlling cell...
10.
Witko-Sarsat V, Thieblemont N
Joint Bone Spine
. 2017 May;
85(2):185-189.
PMID: 28495524
Granulomatosis with polyangiitis (GPA, Wegener granulomatosis) is a systemic autoimmune vasculitis that affects small arteries, arterioles, and capillaries, most notably in the kidneys and lungs. In this disease, proteinase-3 (PR3),...