Nathalie Bernoud-Hubac
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Explore the profile of Nathalie Bernoud-Hubac including associated specialties, affiliations and a list of published articles.
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Recent Articles
31.
Lefils J, Geloen A, Vidal H, Lagarde M, Bernoud-Hubac N
Br J Nutr
. 2010 May;
104(9):1304-12.
PMID: 20487585
Consumption of DHA has numerous beneficial effects, but little is known about these effects during the first few days of the DHA dietary intake. The main objectives of the present...
32.
Bernoud-Hubac N, Al Alam D, Lefils J, Davies S, Amarnath V, Guichardant M, et al.
Biochim Biophys Acta
. 2009 Feb;
1791(4):307-13.
PMID: 19233311
Oxidative stress has been strongly implicated in pathological processes. Isoketals are highly reactive gamma-ketoaldehydes of the isoprostanes pathway of free radical-induced peroxidation of arachidonic acid that are analogous to cyclooxygenase-derived...
33.
Bacot S, Bernoud-Hubac N, Chantegrel B, Deshayes C, Doutheau A, Ponsin G, et al.
J Lipid Res
. 2007 Jan;
48(4):816-25.
PMID: 17220481
Hydroxy-alkenals, such as 4-hydroxy-2(E)-nonenal (4-HNE; from n-6 fatty acids), are degradation products of fatty acid hydroperoxides, including those generated by free radical attack of membrane polyunsaturated fatty acyl moieties. The...
34.
Bernoud-Hubac N, Fay L, Armarnath V, Guichardant M, Bacot S, Davies S, et al.
Free Radic Biol Med
. 2004 Oct;
37(10):1604-11.
PMID: 15477011
Free radicals have been strongly implicated in the pathogenesis of many human diseases. We previously identified the formation of highly reactive gamma-ketoaldehydes, isoketals, in vivo as products of free radical-induced...
35.
Zagol-Ikapitte I, Bernoud-Hubac N, Amarnath V, Roberts 2nd L, Boutaud O, Oates J
Biochemistry
. 2004 May;
43(18):5503-10.
PMID: 15122916
Levuglandins are gamma-keto aldehydes formed by rearrangement of prostaglandin (PG) H(2) in aqueous solution. Levuglandins are highly reactive with primary amines. We had previously characterized adducts formed after reaction of...
36.
Bacot S, Bernoud-Hubac N, Baddas N, Chantegrel B, Deshayes C, Doutheau A, et al.
J Lipid Res
. 2003 Feb;
44(5):917-26.
PMID: 12588949
Lipid oxidation is implicated in a wide range of pathophysiogical disorders, and leads to reactive compounds such as fatty aldehydes, of which the most well known is 4-hydroxy-2E-nonenal (4-HNE) issued...
37.
Bernoud-Hubac N, Roberts 2nd L
Biochemistry
. 2002 Sep;
41(38):11466-71.
PMID: 12234189
Oxidative stress and protein aggregation have been implicated in the pathogenesis of neurodegenerative diseases. The formation of neuroprostanes, isoprostane-like compounds formed from oxidation of docosahexaenoic acid, which is uniquely enriched...
38.
Davies S, Amarnath V, Montine K, Bernoud-Hubac N, Boutaud O, Montine T, et al.
FASEB J
. 2002 Apr;
16(7):715-7.
PMID: 11978738
Oxidative stress can impair proteasome function, both of which are features of neurodegenerative diseases. Inhibition of proteasome function leads to protein accumulation and cell death. We discovered recently the formation...