Nathali Kaushansky
Overview
Explore the profile of Nathali Kaushansky including associated specialties, affiliations and a list of published articles.
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40
Citations
769
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Recent Articles
1.
Kadam A, Shilo S, Naor H, Wainstein A, Brilon Y, Feldman T, et al.
Nucleic Acids Res
. 2024 Nov;
52(22):e106.
PMID: 39607705
We developed Del-read, an algorithm targeting medium-sized deletions (6-100 bp) in short-reads, which are challenging for current variant callers relying on alignment. Our focus was on Micro-Homolog mediated End Joining...
2.
Su M, Fleischer T, Grosheva I, Horev M, Olszewska M, Mattioli C, et al.
iScience
. 2024 Apr;
27(4):109443.
PMID: 38558935
Spliceosome machinery mutations are common early mutations in myeloid malignancies; however, effective targeted therapies against them are still lacking. In the current study, we used an high-throughput drug screen among...
3.
Bacharach T, Kaushansky N, Shlush L
Curr Opin Hematol
. 2023 Dec;
31(2):53-57.
PMID: 38133628
Purpose Of Review: Both aging and reduced diversity at the hematopoietic stem cells (HSCs) level are ubiquitous. What remains unclear is why some individuals develop clonal hematopoiesis (CH), and why...
4.
Legesse A, Kaushansky N, Braunstein I, Saad H, Lederkremer G, Navon A, et al.
Commun Biol
. 2023 Apr;
6(1):385.
PMID: 37031316
Protein quality control is a process in which a protein's folding status is constantly monitored. Mislocalized proteins (MLP), are processed by the various quality control pathways, as they are often...
5.
Kim K, Kim T, Novitzky-Basso I, Lee H, Yoo Y, Ahn J, et al.
Haematologica
. 2023 Feb;
108(7):1817-1826.
PMID: 36727396
Donor clonal hematopoiesis may be transferred to the recipient through allogeneic hematopoietic stem cell transplantation (HSCT), but the potential for adverse long-term impact on transplant outcomes remains unknown. A total...
6.
Tuval A, Brilon Y, Azogy H, Moskovitz Y, Leshkowitz D, Salame T, et al.
Haematologica
. 2022 Feb;
107(11):2548-2561.
PMID: 35199506
Pre-leukemic clones carrying DNMT3A mutations have a selective advantage and an inherent chemoresistance, however the basis for this phenotype has not been fully elucidated. Mutations affecting the gene TP53 occur...
7.
Biezuner T, Brilon Y, Arye A, Oron B, Kadam A, Danin A, et al.
NAR Genom Bioinform
. 2022 Feb;
4(1):lqab125.
PMID: 35156021
Deep targeted sequencing technologies are still not widely used in clinical practice due to the complexity of the methods and their cost. The Molecular Inversion Probes (MIP) technology is cost...
8.
Furer N, Kaushansky N, Shlush L
Nat Med
. 2021 Jun;
27(6):949-950.
PMID: 34099925
No abstract available.
9.
Feldman T, Bercovich A, Moskovitz Y, Chapal-Ilani N, Mitchell A, Medeiros J, et al.
Nat Commun
. 2021 Apr;
12(1):2455.
PMID: 33911081
The mutational mechanisms underlying recurrent deletions in clonal hematopoiesis are not entirely clear. In the current study we inspect the genomic regions around recurrent deletions in myeloid malignancies, and identify...
10.
Shahar Gabay T, Chapal-Ilani N, Moskovitz Y, Biezuner T, Oron B, Brilon Y, et al.
Haematologica
. 2020 Dec;
105(12):2861-2863.
PMID: 33256388
No abstract available.