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Natasha Kushnir

Explore the profile of Natasha Kushnir including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 493
Followers 0
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Recent Articles
1.
Banik S, Kushnir N, Doranz B, Chambers R
MAbs . 2023 Dec; 15(1):2273018. PMID: 38050985
To exploit highly conserved and difficult drug targets, including multipass membrane proteins, monoclonal antibody discovery efforts increasingly rely on the advantages offered by divergent species such as rabbits, camelids, and...
2.
Yusibov V, Kushnir N, Streatfield S
Annu Rev Plant Biol . 2016 Feb; 67:669-701. PMID: 26905655
Monoclonal antibodies (mAbs) have a wide range of modern applications, including research, diagnostic, therapeutic, and industrial uses. Market demand for mAbs is high and continues to grow. Although mammalian systems,...
3.
Streatfield S, Kushnir N, Yusibov V
Plant Biotechnol J . 2015 Sep; 13(8):1136-59. PMID: 26387510
Despite progress in the prevention and treatment of infectious diseases, they continue to present a major threat to public health. The frequency of emerging and reemerging infections and the risk...
4.
Yusibov V, Kushnir N, Streatfield S
Expert Rev Vaccines . 2014 Dec; 14(4):519-35. PMID: 25487788
Influenza infections continue to present a major threat to public health. Traditional modes of influenza vaccine manufacturing are failing to satisfy the global demand because of limited scalability and long...
5.
Guvakova M, Lee W, Furstenau D, Prabakaran I, Li D, Hung R, et al.
Biochem J . 2014 Jul; 463(2):257-70. PMID: 25028810
The Ras-related GTPase Rap1 promotes cell adhesion and migration. Although the significance of Rap1 contribution to cell migration is increasingly being recognized, little is known about the biochemical mechanisms driving...
6.
Yusibov V, Streatfield S, Kushnir N, Roy G, Padmanaban A
Curr Pharm Des . 2013 Feb; 19(31):5574-86. PMID: 23394571
Plants have a demonstrated potential for large-scale, rapid production of recombinant proteins for diverse product applications, including subunit vaccines and monoclonal antibodies. In this field, the accent has recently shifted...
7.
Kushnir N, Streatfield S, Yusibov V
Vaccine . 2012 Nov; 31(1):58-83. PMID: 23142589
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from soluble recombinant antigens by stronger protective immunogenicity associated with the VLP structure. Like parental viruses, VLPs can...
8.
Yusibov V, Streatfield S, Kushnir N
Hum Vaccin . 2011 Feb; 7(3):313-21. PMID: 21346417
In the last few years, plants have become an increasingly attractive platform for recombinant protein production. This builds on two decades of research, starting with transgenic approaches to develop oral...
9.
Shoji Y, Chichester J, Jones M, Manceva S, Damon E, Mett V, et al.
Hum Vaccin . 2011 Jan; 7 Suppl:41-50. PMID: 21266846
In 2009, a novel H1N1 swine influenza virus was isolated from infected humans in Mexico and the United States, and rapidly spread around the world. Another virus, a highly pathogenic...
10.
Dijkstra G, Yuvaraj S, Jiang H, Bun J, Moshage H, Kushnir N, et al.
Inflamm Bowel Dis . 2007 Sep; 13(12):1467-74. PMID: 17879278
Background: Both the role of inducible nitric oxide synthase (iNOS) in the development of inflammatory bowel disease (IBD) as well as the molecular details governing its mucosal induction remain unclear....