Natasha Collinson
Overview
Explore the profile of Natasha Collinson including associated specialties, affiliations and a list of published articles.
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10
Citations
133
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Recent Articles
1.
Ullah M, Rittchen S, Li J, Curren B, Namubiru P, Ahmed T, et al.
Nat Commun
. 2024 Nov;
15(1):10253.
PMID: 39592603
Prostaglandin D2 (PGD2) signals via the DP1 and DP2 receptors. In Phase II trials, DP2 antagonism decreased airway inflammation and airway smooth muscle (ASM) area in moderate-to-severe asthma patients. However,...
2.
MacGregor S, McManus D, Sivakumaran H, Egwang T, Adriko M, Cai P, et al.
EBioMedicine
. 2023 Jul;
94:104730.
PMID: 37487416
Background: Schistosomiasis is a disease that significantly impacts human health in the developing world. Effective diagnostics are urgently needed for improved control of this disease. CRISPR-based technology has rapidly accelerated...
3.
Du X, McManus D, French J, Collinson N, Sivakumaran H, MacGregor S, et al.
Front Immunol
. 2023 Jan;
13:1105719.
PMID: 36713455
Employing the flatworm parasite as a model, we report the first application of CRISPR interference (CRISPRi) in parasitic helminths for loss-of-function studies targeting the gene which encodes the stem cell...
4.
Werder R, Ullah M, Rahman M, Simpson J, Lynch J, Collinson N, et al.
Am J Respir Crit Care Med
. 2021 Dec;
205(3):300-312.
PMID: 34860143
The alarmins IL-33 and HMGB1 (high mobility group box 1) contribute to type 2 inflammation and asthma pathogenesis. To determine whether P2Y-R (P2Y receptor), a purinergic GPCR (G protein-coupled receptor)...
5.
Tu W, McCuaig R, Melino M, Rawle D, Le T, Yan K, et al.
Cell Discov
. 2021 Jul;
7(1):58.
PMID: 34315866
No abstract available.
6.
Collinson N, Snape N, Beagley K, Fantino E, Spann K
Viruses
. 2021 Jun;
13(5).
PMID: 34069223
IFN treatment may be a viable option for treating COPD exacerbations based on evidence of IFN deficiency in COPD. However, in vitro studies have used primarily influenza and rhinoviruses to...
7.
Tu W, McCuaig R, Melino M, Rawle D, Le T, Yan K, et al.
Cell Discov
. 2021 May;
7(1):37.
PMID: 34031383
Treatment options for COVID-19 remain limited, especially during the early or asymptomatic phase. Here, we report a novel SARS-CoV-2 viral replication mechanism mediated by interactions between ACE2 and the epigenetic...
8.
Simpson J, Loh Z, Ullah M, Lynch J, Werder R, Collinson N, et al.
Am J Respir Crit Care Med
. 2020 Feb;
201(11):1358-1371.
PMID: 32105156
: Respiratory syncytial virus (RSV) bronchiolitis causes significant infant mortality. Bronchiolitis is characterized by airway epithelial cell (AEC) death; however, the mode of death remains unknown.: To determine whether necroptosis...
9.
Ullah M, Vicente C, Collinson N, Curren B, Sikder M, Sebina I, et al.
Allergy
. 2019 Jul;
75(2):336-345.
PMID: 31321783
Background: Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (PAG1) is a transmembrane adaptor protein that affects immune receptor signaling in T and B cells. Evidence from genome-wide association studies of asthma...
10.
Baturcam E, Snape N, Yeo T, Schagen J, Thomas E, Logan J, et al.
J Innate Immun
. 2016 Oct;
9(1):52-64.
PMID: 27723652
Asthmatics are highly susceptible to respiratory viral infections, possibly due to impaired innate immunity. However, the exact mechanisms of susceptibility are likely to differ amongst viruses. Therefore, we infected primary...