Natalie N Whitfield
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Explore the profile of Natalie N Whitfield including associated specialties, affiliations and a list of published articles.
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8
Citations
317
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Recent Articles
1.
Lu J, Ter Voert M, Unal M, Whitfield N, Liesenfeld O, Ter Maaten J, et al.
Intensive Care Med Exp
. 2025 Feb;
13(1):21.
PMID: 39982589
Background: Early sepsis diagnosis is essential to allow timely initiation of adequate care. The TriVerity™ Test, performed on the Myrna™ Instrument, is the first rapid high-multiplex host-response mRNA diagnostic test...
2.
Whitfield N, Hogan C, Chenoweth J, Hansen J, Hsu E, Humphries R, et al.
Diagn Microbiol Infect Dis
. 2024 Jun;
110(1):116382.
PMID: 38850687
In absence of a "gold standard", a standardized clinical adjudication process was developed for a registrational trial of a transcriptomic host response (HR) test. Two physicians independently reviewed clinical data...
3.
Wolk D, Young S, Whitfield N, Reid J, Thornberg A, Carroll K, et al.
J Clin Microbiol
. 2021 Jul;
59(9):e0248420.
PMID: 34232066
Bacteremia can progress to septic shock and death without appropriate medical intervention. Increasing evidence supports the role of molecular diagnostic panels in reducing the clinical impact of these infections through...
4.
Zhen W, Whitfield N, Smith E, Shaw C, Ivy C, Douglas C, et al.
J Appl Lab Med
. 2021 Apr;
6(5):1213-1220.
PMID: 33893500
Introduction: The ePlex® SARS-CoV-2 emergency use authorization (EUA) test is a cartridge-based assay for the detection of SARS-CoV-2 in nasopharyngeal specimens. Since performance data has been previously published on this...
5.
Tamma P, Smith T, Adebayo A, Karaba S, Jacobs E, Wakefield T, et al.
J Clin Microbiol
. 2021 Apr;
59(6).
PMID: 33827899
Understanding bacterial species at greatest risk for harboring genes is necessary to guide antibiotic treatment. We identified the species-specific prevalence of genes in Gram-negative clinical isolates from the United States....
6.
Zhang S, Carroll K, Lewis S, Totten M, Mead P, Samuel L, et al.
J Clin Microbiol
. 2020 Feb;
58(5).
PMID: 32075904
Routine identification of fungal pathogens from positive blood cultures by culture-based methods can be time-consuming, delaying treatment with appropriate antifungal agents. The GenMark Dx ePlex investigational use only blood culture...
7.
Carroll K, Reid J, Thornberg A, Whitfield N, Trainor D, Lewis S, et al.
J Clin Microbiol
. 2020 Jan;
58(4).
PMID: 31996444
Rapid identification from positive blood cultures is standard of care (SOC) in many clinical microbiology laboratories. The GenMark Dx ePlex Blood Culture Identification Gram-Positive (BCID-GP) Panel is a multiplex nucleic...
8.
Whitfield N, Byrne B, Swanson M
Infect Immun
. 2009 Oct;
78(1):423-32.
PMID: 19841075
Legionella pneumophila, a motile opportunistic pathogen of humans, is restricted from replicating in the lungs of C57BL/6 mice. Resistance of mouse macrophages to L. pneumophila depends on recognition of cytosolic...
9.
Molofsky A, Byrne B, Whitfield N, Madigan C, Fuse E, Tateda K, et al.
J Exp Med
. 2006 Apr;
203(4):1093-104.
PMID: 16606669
To restrict infection by Legionella pneumophila, mouse macrophages require Naip5, a member of the nucleotide-binding oligomerization domain leucine-rich repeat family of pattern recognition receptors, which detect cytoplasmic microbial products. We...