Natalie Lefort
Overview
Explore the profile of Natalie Lefort including associated specialties, affiliations and a list of published articles.
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16
Citations
621
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0
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Recent Articles
1.
Lefort N, LeBlanc R, Surette M
Nutrients
. 2017 Mar;
9(3).
PMID: 28287415
(Ahiflower) oil is a dietary oil rich in stearidonic acid (20% SDA; 18:4 -3). The present randomized, double blind, placebo-controlled clinical trial investigated the effects of three Ahiflower oil dosages...
2.
Dounia D, Andrea B, Lefort N, Van Geest J
Ecotoxicol Environ Saf
. 2016 Sep;
134P1:106-115.
PMID: 27591805
In Atlantic Canada and other salmon-growing regions, treatment of sea lice infestations in salmon aquaculture is necessary to protect fish health. The product Salmosan®, which contains the organophosphate azamethiphos as...
3.
Lefort N, LeBlanc R, Giroux M, Surette M
J Nutr Sci
. 2016 Jan;
5:e2.
PMID: 26793308
Enrichment of tissues with ≥20-carbon n-3 PUFA like EPA is associated with positive cardiovascular outcomes. Stearidonic acid (SDA; 18 : 4n-3) and α-linolenic acid (ALA; 18 : 3n-3) are plant-derived...
4.
Mielke C, Lefort N, McLean C, Cordova J, Langlais P, Bordner A, et al.
Biochemistry
. 2014 Jun;
53(23):3817-29.
PMID: 24884163
Proteomics techniques have revealed that lysine acetylation is abundant in mitochondrial proteins. This study was undertaken (1) to determine the relationship between mitochondrial protein acetylation and insulin sensitivity in human...
5.
Lefort N, Brown A, Lloyd V, Ouellette R, Touaibia M, Culf A, et al.
J Pharm Biomed Anal
. 2013 Oct;
93:77-85.
PMID: 24074721
Metabolomics analysis was used to determine the effect of two well known, non-proprietary metabolic modulators, dichloroacetate and allopurinol on breast cancer cell lines. Dichloroacetate, a pyruvate dehydrogenase kinase inhibitor and...
6.
Ghosh S, Lertwattanarak R, Lefort N, Molina-Carrion M, Joya-Galeana J, Bowen B, et al.
Diabetes
. 2011 Jun;
60(8):2051-60.
PMID: 21677280
Objective: Aging increases the risk of developing impaired glucose tolerance (IGT) and type 2 diabetes. It has been proposed that increased reactive oxygen species (ROS) generation by dysfunctional mitochondria could...
7.
Braden B, Garcia A, Mennenga S, Prokai L, Villa S, Acosta J, et al.
Psychopharmacology (Berl)
. 2011 May;
218(2):405-18.
PMID: 21562760
Rationale: The synthetic progestin medroxyprogesterone acetate (MPA), widely used in hormone therapy (HT) and as the contraceptive Depo Provera, is implicated in detrimental cognitive effects in women. Recent evidence in...
8.
Geetha T, Langlais P, Luo M, Mapes R, Lefort N, Chen S, et al.
J Am Soc Mass Spectrom
. 2011 Apr;
22(3):457-66.
PMID: 21472564
Protein-protein interactions are key to most cellular processes. Tandem mass spectrometry (MS/MS)-based proteomics combined with co-immunoprecipitation (CO-IP) has emerged as a powerful approach for studying protein complexes. However, a majority...
9.
Lefort N, Glancy B, Bowen B, Willis W, Bailowitz Z, De Filippis E, et al.
Diabetes
. 2010 Aug;
59(10):2444-52.
PMID: 20682693
Objective: The contribution of mitochondrial dysfunction to skeletal muscle insulin resistance remains elusive. Comparative proteomics are being applied to generate new hypotheses in human biology and were applied here to...
10.
Civitarese A, MacLean P, Carling S, Kerr-Bayles L, McMillan R, Pierce A, et al.
Cell Metab
. 2010 May;
11(5):412-26.
PMID: 20444421
Type 2 diabetes mellitus (T2DM) and aging are characterized by insulin resistance and impaired mitochondrial energetics. In lower organisms, remodeling by the protease pcp1 (PARL ortholog) maintains the function and...