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Natalie E Nieuwenhuizen

Explore the profile of Natalie E Nieuwenhuizen including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 524
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Recent Articles
1.
Batliner M, Schumacher F, Wigger D, Vivas W, Prell A, Fohmann I, et al.
mBio . 2024 Jul; 15(8):e0073224. PMID: 38953353
an opportunistic fungal pathogen, produces the quorum-sensing molecule farnesol, which we have shown alters the transcriptional response and phenotype of human monocyte-derived dendritic cells (DCs), including their cytokine secretion and...
2.
Nieuwenhuizen N, Nouailles G, Sutherland J, Zyla J, Pasternack A, Heyckendorf J, et al.
mBio . 2024 Feb; 15(3):e0340823. PMID: 38376260
Importance: Tuberculosis remains the leading cause of death by a bacterial pathogen. The etiologic agent of tuberculosis, , can remain dormant in the infected host for years before causing disease....
3.
Figl J, Kohler H, Wedlich N, Liebler-Tenorio E, Grode L, Parzmair G, et al.
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36982586
A more effective vaccine against tuberculosis than (BCG) is urgently needed. BCG derived recombinant VPM1002 has been found to be more efficacious and safer than the parental strain in mice...
4.
Liebler-Tenorio E, Heyl J, Wedlich N, Figl J, Kohler H, Krishnamoorthy G, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36232295
Tuberculous granulomas are highly dynamic structures reflecting the complex host-mycobacterium interactions. The objective of this study was to compare granuloma development at the site of vaccination with BCG and its...
5.
Nieuwenhuizen N, Evans J
Int J Mol Sci . 2022 Jul; 23(13). PMID: 35806210
Tuberculosis (TB), caused by the bacillus , remains a leading cause of death by infectious disease, overshadowed only recently by the COVID-19 pandemic [...].
6.
Belnoue E, Vogelzang A, Nieuwenhuizen N, Krzyzaniak M, Darbre S, Kreutzfeldt M, et al.
Int J Mol Sci . 2022 Mar; 23(5). PMID: 35269842
() represents a major burden to global health, and refined vaccines are needed. Replication-deficient lymphocytic choriomeningitis virus (rLCMV)-based vaccine vectors against cytomegalovirus have proven safe for human use and elicited...
7.
Nieuwenhuizen N, Zyla J, Zedler U, Bandermann S, Abu Abed U, Brinkmann V, et al.
Vaccine . 2021 Oct; 39(50):7253-7264. PMID: 34602301
BCG - the only available vaccine against tuberculosis (TB) - was first given to babies 100 years ago in 1921. While it is effective against TB meningitis and disseminated TB,...
8.
Dorhoi A, Glaria E, Garcia-Tellez T, Nieuwenhuizen N, Zelinskyy G, Favier B, et al.
Cancer Immunol Immunother . 2018 Dec; 68(4):673-685. PMID: 30569204
Many pathogens, ranging from viruses to multicellular parasites, promote expansion of MDSCs, which are myeloid cells that exhibit immunosuppressive features. The roles of MDSCs in infection depend on the class...
9.
Govender M, Hurdayal R, Martinez-Salazar B, Gqada K, Pillay S, Gcanga L, et al.
Infect Immun . 2018 Oct; 86(12). PMID: 30275010
The skin microenvironment at the site of infection plays a role in the early events that determine protective T helper 1/type 1 immune responses during cutaneous leishmaniasis (CL) infection. During...
10.
Nieuwenhuizen N, Kaufmann S
Front Immunol . 2018 Feb; 9:121. PMID: 29459859
Tuberculosis (TB), caused by the intracellular bacterium (Mtb), remains a major health threat. A live, attenuated mycobacterium known as Bacille Calmette-Guérin (BCG), derived from the causative agent of cattle TB,...