Jennifer C Hoving
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Explore the profile of Jennifer C Hoving including associated specialties, affiliations and a list of published articles.
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12
Citations
267
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Recent Articles
1.
Mbangiwa T, Sturny-Leclere A, Lechiile K, Kajanga C, Boyer-Chammard T, Hoving J, et al.
Lancet Microbe
. 2024 Feb;
5(3):e261-e271.
PMID: 38342110
Background: HIV-associated cryptococcal meningitis is the second leading cause of AIDS-related deaths, with a 10-week mortality rate of 25-30%. Fungal load assessed by colony-forming unit (CFU) counts is used as...
2.
Azimova D, Herrera N, Duvenage L, Voorhies M, Rodriguez R, English B, et al.
PLoS Pathog
. 2022 Jun;
18(6):e1010417.
PMID: 35731824
Intracellular pathogens secrete effectors to manipulate their host cells. Histoplasma capsulatum (Hc) is a fungal intracellular pathogen of humans that grows in a yeast form in the host. Hc yeasts...
3.
Armstrong-James D, Bicanic T, Brown G, Hoving J, Meintjes G, Nielsen K
Trends Microbiol
. 2017 Apr;
25(6):428-430.
PMID: 28454846
Opportunistic fungal infections continue to take an unacceptably heavy toll on the most disadvantaged living with HIV-AIDS, and are a major driver for HIV-related deaths. At the second EMBO Workshop...
4.
Hoving J, Cutler A, Leeto M, Horsnell W, Dewals B, Nieuwenhuizen N, et al.
Gut
. 2017 Mar;
66(11):2037-2039.
PMID: 28246312
No abstract available.
5.
Wilson G, Marakalala M, Hoving J, van Laarhoven A, Drummond R, Kerscher B, et al.
Cell Host Microbe
. 2015 Feb;
17(2):252-9.
PMID: 25674984
The interaction of microbes with pattern recognition receptors (PRRs) is essential for protective immunity. While many PRRs that recognize mycobacteria have been identified, none is essentially required for host defense...
6.
Hurdayal R, Nieuwenhuizen N, Revaz-Breton M, Smith L, Hoving J, Parihar S, et al.
PLoS Pathog
. 2013 Nov;
9(10):e1003699.
PMID: 24204259
In BALB/c mice, susceptibility to infection with the intracellular parasite Leishmania major is driven largely by the development of T helper 2 (Th2) responses and the production of interleukin (IL)-4...
7.
Horsnell W, Darby M, Hoving J, Nieuwenhuizen N, McSorley H, Ndlovu H, et al.
PLoS Pathog
. 2013 Nov;
9(10):e1003662.
PMID: 24204255
In this study, B cell function in protective T(H)2 immunity against N. brasiliensis infection was investigated. Protection against secondary infection depended on IL-4Rα and IL-13; but not IL-4. Protection did...
8.
Marakalala M, Williams D, Hoving J, Engstad R, Netea M, Brown G
Microbes Infect
. 2013 Mar;
15(6-7):511-5.
PMID: 23518266
β-Glucans are known for their ability to trigger both protective and damaging immune responses. Here we have explored the role of the beta-glucan receptor Dectin-1 in archetypical models of protective...
9.
Hoving J, Kirstein F, Nieuwenhuizen N, Fick L, Hobeika E, Reth M, et al.
Gastroenterology
. 2011 Oct;
142(1):96-108.
PMID: 21983080
Background & Aims: Induction of colitis in mice by administration of oxazolone is mediated by T-helper (Th) 2 cells and has features of human ulcerative colitis. We investigated whether activation...
10.
Dewals B, Hoving J, Horsnell W, Brombacher F
Eur J Immunol
. 2010 Sep;
40(10):2837-47.
PMID: 20821727
Host protection to helminth infection requires IL-4 receptor α chain (IL-4Rα) signalling and the establishment of finely regulated Th2 responses. In the current study, the role of IL-4Rα-responsive T cells...