Natalie De Ruyck
Overview
Explore the profile of Natalie De Ruyck including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
1473
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0
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Recent Articles
1.
Blauwblomme M, Gevaert P, Van Nevel S, Riemann S, Vandewalle E, Holtappels G, et al.
Front Allergy
. 2024 Nov;
5:1484931.
PMID: 39552698
Context: Recent insights into type 2 inflammation have led to the development of monoclonal antibody therapies for severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). Despite add-on therapy with...
2.
Declercq J, Gerlo S, Van Nevel S, De Ruyck N, Holtappels G, Delesie L, et al.
Sci Transl Med
. 2024 Oct;
16(770):eadn2364.
PMID: 39441904
To prevent infection by respiratory viruses and consequently limit virus circulation, vaccines need to promote mucosal immunity. The extent to which the currently used messenger RNA (mRNA)-based COVID-19 vaccines induce...
3.
Xu Z, Huang Y, Meese T, Van Nevel S, Holtappels G, Vanhee S, et al.
Clin Immunol
. 2023 Sep;
256:109791.
PMID: 37769787
Uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with elevated levels of type 2 inflammatory cytokines and raised immunoglobulin concentrations in nasal polyp tissue. By using single-cell RNA...
4.
Krysko O, Korsakova D, Teufelberger A, De Meyer A, Steels J, De Ruyck N, et al.
Front Immunol
. 2023 May;
14:1040493.
PMID: 37153601
Background: Recent studies strongly implicated mast cell-derived proteases as regulators of IL-33 activity by enzymatic cleavage in its central domain. A better understanding of the role of mast cell proteases...
5.
Declercq J, Tobback E, Vanhee S, De Ruyck N, Gerlo S, Gevaert P, et al.
Allergy
. 2021 Sep;
77(1):304-307.
PMID: 34543444
No abstract available.
6.
Van Nevel S, van Ovost J, Holtappels G, De Ruyck N, Zhang N, Braun H, et al.
Front Immunol
. 2021 Sep;
12:677848.
PMID: 34484177
Future precision medicine requires further clarifying the mechanisms of inflammation in the severe endotypes of chronic airway diseases such as asthma and chronic rhinosinusitis (CRS). The presence of neutrophils in...
7.
Gevaert P, De Craemer J, De Ruyck N, Rottey S, de Hoon J, Hellings P, et al.
J Allergy Clin Immunol
. 2021 Jun;
149(1):189-199.
PMID: 34126156
Background: The efficacy of an allergen-specific IgG cocktail to treat cat allergy suggests that allergen-specific IgG may be a major protective mechanism elicited by allergen immunotherapy. Objectives: Extending these findings,...
8.
Delemarre T, De Ruyck N, Holtappels G, Bachert C, Gevaert E
Clin Transl Allergy
. 2020 Dec;
10(1):41.
PMID: 33292477
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a Th2 biased inflammation, associated with nasal colonization of Staphylococcus (S.) aureus. Interleukin (IL)-9 is a pro-inflammatory Th2 cytokine with a pivotal role...
9.
Teufelberger A, Van Nevel S, Hulpiau P, Nordengrun M, Savvides S, De Graeve S, et al.
Front Immunol
. 2020 Oct;
11:582044.
PMID: 33072128
( can secrete a broad range of virulence factors, among which staphylococcal serine protease-like proteins (Spls) have been identified as bacterial allergens. The allergen serine protease-like protein D (SplD) induces...
10.
Delemarre T, Holtappels G, De Ruyck N, Zhang N, Nauwynck H, Bachert C, et al.
J Allergy Clin Immunol
. 2020 Sep;
147(1):179-188.e2.
PMID: 32949587
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally associated with severe type 2 immune reactions in the white population. However, recent findings suggest an additional role for neutrophils in...