Natalie C Holt
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Explore the profile of Natalie C Holt including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
164
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Recent Articles
1.
Mayfield D, Holt N
Am J Physiol Cell Physiol
. 2024 Dec;
328(2):C528-C540.
PMID: 39726260
The optimum length for force generation () increases as activation is reduced, challenging classic theories of muscle contraction. Although the activation dependence of is seemingly consistent with length-dependent Ca sensitivity,...
2.
Nguyen A, Leong K, Holt N
J Exp Biol
. 2024 Dec;
228(2).
PMID: 39690956
The jaw muscles of the southern alligator lizard, Elgaria multicarinata, are used in prolonged mate-holding behavior, and also to catch fast prey. In both males and females, these muscles exhibit...
3.
Castro A, Nguyen A, Ahmed S, Garland Jr T, Holt N
Ecol Evol Physiol
. 2024 Sep;
97(4):191-208.
PMID: 39270325
AbstractMuscle-tendon unit (MTU) morphology and physiology are likely major determinants of locomotor performance and therefore Darwinian fitness. However, the relationships between underlying traits, performance, and fitness are complicated by phenomena...
4.
Labonte D, Holt N
J Exp Biol
. 2024 Sep;
227(21).
PMID: 39234652
Muscle is the universal agent of animal movement, and limits to muscle performance are therefore an integral aspect of animal behaviour, ecology and evolution. A mechanical perspective on movement makes...
5.
Dhawale N, Labonte D, Holt N
J R Soc Interface
. 2024 May;
21(214):20230658.
PMID: 38774960
Skeletal muscle powers animal movement through interactions between the contractile proteins, actin and myosin. Structural variation contributes greatly to the variation in mechanical performance observed across muscles. In vertebrates, gross...
6.
Castro A, Garland T, Ahmed S, Holt N
J Exp Biol
. 2022 Nov;
225(23).
PMID: 36408738
A trade-off between locomotor speed and endurance occurs in various taxa, and is thought to be underpinned by a muscle-level trade-off. Among four replicate high runner (HR) lines of mice,...
7.
Labonte D, Holt N
Curr Biol
. 2022 Jun;
32(12):R661-R666.
PMID: 35728549
Movement is an integral part of animal biology. It enables organisms to escape from danger, acquire food, and perform courtship displays. Changing the speed or vertical position of a body...
8.
Gordon J, Holt N, Biewener A, Daley M
Elife
. 2020 Jun;
9.
PMID: 32573432
Animals must integrate feedforward, feedback and intrinsic mechanical control mechanisms to maintain stable locomotion. Recent studies of guinea fowl () revealed that the distal leg muscles rapidly modulate force and...
9.
Eng C, Konow N, Tijs C, Holt N, Biewener A
J Exp Biol
. 2019 Nov;
222(Pt 24).
PMID: 31753907
Muscle function changes to meet the varying mechanical demands of locomotion across different gait and grade conditions. A muscle's work output is determined by time-varying patterns of neuromuscular activation, muscle...
10.
Roberts T, Eng C, Sleboda D, Holt N, Brainerd E, Stover K, et al.
Physiology (Bethesda)
. 2019 Oct;
34(6):402-408.
PMID: 31577172
Muscle contraction is a three-dimensional process, as anyone who has observed a bulging muscle knows. Recent studies suggest that the three-dimensional nature of muscle contraction influences its mechanical output. Shape...