Natalia Yanguas-Casas
Overview
Explore the profile of Natalia Yanguas-Casas including associated specialties, affiliations and a list of published articles.
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24
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Recent Articles
11.
Mecha M, Yanguas-Casas N, Feliu A, Mestre L, Carrillo-Salinas F, Riecken K, et al.
J Neuroinflammation
. 2020 Mar;
17(1):88.
PMID: 32192522
Background: The participation of microglia in CNS development and homeostasis indicate that these cells are pivotal for the regeneration that occurs after demyelination. The clearance of myelin debris and the...
12.
Yanguas-Casas N, Ojalvo-Sanz A, Martinez-Vazquez A, Goneau M, Gilbert M, Nieto-Sampedro M, et al.
Toxicol Appl Pharmacol
. 2019 Jun;
377:114627.
PMID: 31202640
In many neuropathologies activated microglia and macrophages cause neurotoxicity and prolong the inflammatory response. We have previously characterized the glycosphingolipid Neurostatin (Nst), which potentially reduces these detrimental mechanisms. Nst, isolated...
13.
Crespo-Castrillo A, Yanguas-Casas N, Arevalo M, Azcoitia I, Barreto G, Garcia-Segura L
Mol Neurobiol
. 2018 Mar;
55(11):8651-8667.
PMID: 29582398
Previous studies have shown that estradiol reduces reactive gliosis after a stab wound injury in the cerebral cortex. Since the therapeutic use of estradiol is limited by its peripheral hormonal...
14.
Yanguas-Casas N, Crespo-Castrillo A, de Ceballos M, Chowen J, Azcoitia I, Arevalo M, et al.
Glia
. 2017 Nov;
66(3):522-537.
PMID: 29139169
Sex differences in the incidence, clinical manifestation, disease course, and prognosis of neurological diseases, such as autism spectrum disorders or Alzheimer's disease, have been reported. Obesity has been postulated as...
15.
Romero-Ramirez L, Nieto-Sampedro M, Yanguas-Casas N
Neural Regen Res
. 2017 Mar;
12(1):62-63.
PMID: 28250744
No abstract available.
16.
Yanguas-Casas N, Barreda-Manso M, Nieto-Sampedro M, Romero-Ramirez L
J Cell Physiol
. 2016 Dec;
232(8):2231-2245.
PMID: 27987324
Bile acids are steroid acids found in the bile of mammals. The bile acid conjugate tauroursodeoxycholic acid (TUDCA) is neuroprotective in different animal models of stroke and neurological diseases. We...
17.
Barreda-Manso M, Yanguas-Casas N, Nieto-Sampedro M, Romero-Ramirez L
J Cell Physiol
. 2016 Oct;
232(6):1501-1510.
PMID: 27753092
Following a central nervous system (CNS) injury, restoration of the blood-brain barrier (BBB) integrity is essential for recovering homeostasis. When this process is delayed or impeded, blood substances and cells...
18.
Yanguas-Casas N, Barreda-Manso M, Perez-Rial S, Nieto-Sampedro M, Romero-Ramirez L
Mol Neurobiol
. 2016 Oct;
54(9):6737-6749.
PMID: 27744574
The bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in various animal models of neuropathologies. We have previously shown the anti-inflammatory properties of TUDCA in an animal model...
19.
Yang R, Masters A, Fortner K, Champagne D, Yanguas-Casas N, Silberger D, et al.
J Exp Med
. 2016 Sep;
213(11):2281-2291.
PMID: 27670591
IL-6 is known to contribute to the differentiation of CD4 T cells into different subsets of effector T helper cells. Less is known about the potential of IL-6 in regulating...
20.
Romero-Ramirez L, Garcia-Alvarez I, Casas J, Barreda-Manso M, Yanguas-Casas N, Nieto-Sampedro M, et al.
Biochem Pharmacol
. 2015 Jul;
97(2):158-72.
PMID: 26206186
We designed and synthesized two anomeric oleyl glucosaminides as anti-cancer agents where the presence of a trifluoroacetyl group close to the anomeric center makes them resistant to hydrolysis by hexosaminidases....