Natalia Izotova
Overview
Explore the profile of Natalia Izotova including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
345
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Gerber J, Russ J, Chandrasekar V, Offermann N, Lee H, Spear S, et al.
Nat Cell Biol
. 2022 Jan;
24(1):123.
PMID: 34983954
No abstract available.
2.
Gerber J, Russ J, Chandrasekar V, Offermann N, Lee H, Spear S, et al.
Nat Cell Biol
. 2021 Dec;
23(12):1224-1239.
PMID: 34876685
Defective silencing of retrotransposable elements has been linked to inflammageing, cancer and autoimmune diseases. However, the underlying mechanisms are only partially understood. Here we implicate the histone H3.3 chaperone Daxx,...
3.
Biasco L, Izotova N, Rivat C, Ghorashian S, Richardson R, Guvenel A, et al.
Nat Cancer
. 2021 Aug;
2(6):629-642.
PMID: 34345830
Low-affinity CD19 chimeric antigen receptor (CAR) T cells display enhanced expansion and persistence, enabling fate tracking through integration site analysis. Here we show that integration sites from early (1 month)...
4.
Kohn D, Booth C, Shaw K, Xu-Bayford J, Garabedian E, Trevisan V, et al.
N Engl J Med
. 2021 May;
384(21):2002-2013.
PMID: 33974366
Background: Severe combined immunodeficiency due to adenosine deaminase (ADA) deficiency (ADA-SCID) is a rare and life-threatening primary immunodeficiency. Methods: We treated 50 patients with ADA-SCID (30 in the United States...
5.
Izotova N, Rivat C, Baricordi C, Blanco E, Pellin D, Watt E, et al.
Nat Commun
. 2021 Mar;
12(1):1622.
PMID: 33712608
Our mathematical model of integration site data in clinical gene therapy supported the existence of long-term lymphoid progenitors capable of surviving independently from hematopoietic stem cells. To date, no experimental...
6.
Blanco E, Izotova N, Booth C, Thrasher A
Front Immunol
. 2020 Dec;
11:608653.
PMID: 33329605
X-linked severe immunodeficiency disease (SCID-X1) is an inherited, rare, and life-threating disease. The genetic origin is a defect in the interleukin 2 receptor γ chain () gene and patients are...
7.
Kohn D, Booth C, Kang E, Pai S, Shaw K, Santilli G, et al.
Nat Med
. 2020 Jan;
26(2):200-206.
PMID: 31988463
Chronic granulomatous disease (CGD) is a rare inherited disorder of phagocytic cells. We report the initial results of nine severely affected X-linked CGD (X-CGD) patients who received ex vivo autologous...
8.
Ryan P, Sumaria N, Holland C, Bradford C, Izotova N, Grandjean C, et al.
Proc Natl Acad Sci U S A
. 2016 Dec;
113(50):14378-14383.
PMID: 27911793
Human γδ T cells display potent responses to pathogens and malignancies. Of particular interest are those expressing a γδ T-cell receptor (TCR) incorporating TCRδ-chain variable-region-2 [Vδ2], which are activated by...