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Nastaran Behzadnia

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Recent Articles
1.
Behzadnia N, Golas M, Hartmuth K, Sander B, Kastner B, Deckert J, et al.
EMBO J . 2007 Mar; 26(6):1737-48. PMID: 17332742
Little is known about the higher-order structure of prespliceosomal A complexes, in which pairing of the pre-mRNA's splice sites occurs. Here, human A complexes were isolated under physiological conditions by...
2.
Behzadnia N, Hartmuth K, Will C, Luhrmann R
RNA . 2006 Aug; 12(9):1738-46. PMID: 16880538
Two different models currently exist for the assembly pathway of the spliceosome, namely, the traditional model, in which spliceosomal snRNPs associate in a stepwise, ordered manner with the pre-mRNA, and...
3.
Deckert J, Hartmuth K, Boehringer D, Behzadnia N, Will C, Kastner B, et al.
Mol Cell Biol . 2006 Jul; 26(14):5528-43. PMID: 16809785
The spliceosomal B complex is the substrate that undergoes catalytic activation leading to catalysis of pre-mRNA splicing. Previous characterization of this complex was performed in the presence of heparin, which...
4.
Dybkov O, Will C, Deckert J, Behzadnia N, Hartmuth K, Luhrmann R
Mol Cell Biol . 2006 Mar; 26(7):2803-16. PMID: 16537922
The 17S U2 snRNP plays an essential role in branch point selection and catalysis during pre-mRNA splicing. Much remains to be learned about the molecular architecture of the U2 snRNP,...