Nareg Roubinian
Overview
Explore the profile of Nareg Roubinian including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
868
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Recent Articles
1.
DAlessandro A, Keele G, Hay A, Hay A, Nemkov T, Earley E, et al.
Blood
. 2024 Nov;
145(7):765-783.
PMID: 39541586
Red blood cell (RBC) metabolism regulates hemolysis during aging in vivo and in the blood bank. However, the genetic underpinnings of RBC metabolic heterogeneity and extravascular hemolysis at population scale...
2.
Willemse R, Grobler C, Murphy E, Roubinian N, Colemen C, Machaba S, et al.
Vox Sang
. 2024 Sep;
119(11):1166-1173.
PMID: 39260452
Background And Objectives: South Africa has a high prevalence of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) and to a lesser extent human T-lymphotropic virus (HTLV). Each of...
3.
Nemkov T, Stephenson D, Earley E, Keele G, Hay A, Key A, et al.
Cell Metab
. 2024 Jul;
36(9):1979-1997.e13.
PMID: 38964323
Mature red blood cells (RBCs) lack mitochondria and thus exclusively rely on glycolysis to generate adenosine triphosphate (ATP) during aging in vivo or storage in blood banks. Here, we leveraged...
4.
Xu J, Neeman E, Thai K, Mishra P, Schlessinger D, Clancy H, et al.
J Hosp Med
. 2024 Apr;
19(6):449-459.
PMID: 38606546
Background: Hospital-acquired venous thromboembolism (HA VTE) is a preventable complication in hospitalized patients. Objective: We aimed to examine the use of pharmacologic prophylaxis (pPPX) and compare two risk assessment methods...
5.
Nemkov T, Key A, Stephenson D, Earley E, Keele G, Hay A, et al.
Blood
. 2024 Mar;
143(24):2517-2533.
PMID: 38513237
Recent large-scale multiomics studies suggest that genetic factors influence the chemical individuality of donated blood. To examine this concept, we performed metabolomics analyses of 643 blood units from volunteers who...
6.
Nemkov T, Stephenson D, Earley E, Keele G, Hay A, Key A, et al.
bioRxiv
. 2024 Jan;
PMID: 38260479
Etoc And Highlights: Highlights: Blood donor age and sex affect glycolysis in stored RBCs from 13,029 volunteers;Ancestry, genetic polymorphisms in PFKP, HK1, CD38/BST1 influence RBC glycolysis;Modeled PFKP effects relate to...
7.
Li N, Pham T, Cheng C, McElfresh D, Metcalf R, Russell W, et al.
Transfus Med Rev
. 2023 Nov;
37(4):150768.
PMID: 37980192
Use of data-driven methodologies in enhancing blood transfusion practices is rising, leveraging big data, machine learning, and optimization techniques to improve demand forecasting and supply chain management. This review used...
8.
Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, et al.
Blood
. 2023 Nov;
143(5):456-472.
PMID: 37976448
In the field of transfusion medicine, the clinical relevance of the metabolic markers of the red blood cell (RBC) storage lesion is incompletely understood. Here, we performed metabolomics of RBC...
9.
van den Berg K, Vermeulen M, Bakkour S, Stone M, Jacobs G, Nyoni C, et al.
Viruses
. 2022 Nov;
14(11).
PMID: 36366424
Blood donations in South Africa are tested for HIV RNA using individual donation NAT (ID-NAT), allowing detection and rapid antiretroviral therapy (ART) of acute HIV infections. We enrolled a cohort...
10.
Carson J, Stanworth S, Dennis J, Trivella M, Roubinian N, Fergusson D, et al.
Cochrane Database Syst Rev
. 2021 Dec;
12:CD002042.
PMID: 34932836
Background: The optimal haemoglobin threshold for use of red blood cell (RBC) transfusions in anaemic patients remains an active field of research. Blood is a scarce resource, and in some...