Narasimhan Kothandaraman
Overview
Explore the profile of Narasimhan Kothandaraman including associated specialties, affiliations and a list of published articles.
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13
Citations
330
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Recent Articles
1.
Cremaschi A, De Iorio M, Kothandaraman N, Yap F, Thway Tint M, Eriksson J
Stat Med
. 2024 Jan;
43(6):1135-1152.
PMID: 38197220
The prevalence of chronic non-communicable diseases such as obesity has noticeably increased in the last decade. The study of these diseases in early life is of paramount importance in determining...
2.
Mei-Ling Tan K, Tint M, Kothandaraman N, Yap F, Godfrey K, Lee Y, et al.
Int J Obes (Lond)
. 2022 Feb;
46(6):1128-1137.
PMID: 35173282
Background: The tryptophan-kynurenine (KYN) pathway is linked to obesity-related systemic inflammation and metabolic health. The pathway generates multiple metabolites, with little available data on their relationships to early markers of...
3.
The Kynurenine Pathway Metabolites in Cord Blood Positively Correlate With Early Childhood Adiposity
Mei-Ling Tan K, Tint M, Kothandaraman N, Michael N, Sadananthan S, Velan S, et al.
J Clin Endocrinol Metab
. 2022 Feb;
107(6):e2464-e2473.
PMID: 35150259
Context: The kynurenine pathway generates metabolites integral to energy metabolism, neurotransmission, and immune function. Circulating kynurenine metabolites positively correlate with adiposity in children and adults, yet it is not known...
4.
Kothandaraman N, Rengaraj A, Xue B, Yew W, Velan S, Karnani N, et al.
Am J Physiol Endocrinol Metab
. 2020 Nov;
320(1):E139-E150.
PMID: 33236920
The current COVID-19 pandemic is probably the worst the world has ever faced since the start of the new millennium. Although the respiratory system is the most prominent target of...
5.
Migliavacca E, Tay S, Patel H, Sonntag T, Civiletto G, McFarlane C, et al.
Nat Commun
. 2019 Dec;
10(1):5808.
PMID: 31862890
The causes of impaired skeletal muscle mass and strength during aging are well-studied in healthy populations. Less is known on pathological age-related muscle wasting and weakness termed sarcopenia, which directly...
6.
Kothandaraman N, Agarwal A, Abu-Elmagd M, Al-Qahtani M
NPJ Genom Med
. 2017 Dec;
1:16023.
PMID: 29263816
Idiopathic male infertility (IMI) affects nearly 10-15% of men in their prime reproductive age. More than 500 target genes were postulated to be associated with this disease condition through various...
7.
Pushparaj P, Rasool M, Naseer M, Damiati L, Kothandaraman N, Gauthaman K, et al.
Bioinformation
. 2015 Mar;
11(1):43-6.
PMID: 25780280
Anaphylaxis is a sudden immune reaction against an allergen that can potentially lead to Anaphylactic Shock (AS). This immune reaction is characterized by an increase in Immunoglobulin-E (IgE) type of...
8.
Baig S, Kothandaraman N, Manikandan J, Rong L, Ee K, Hill J, et al.
Clin Proteomics
. 2014 Dec;
11(1):40.
PMID: 25469110
Background: Placental syncytiotrophoblast microvesicles (STBM) are shed into the maternal circulation during normal pregnancy. STBM circulate in significantly increased amounts in preeclampsia (PE) and are considered to be among contributors...
9.
Ponnusamy S, Zhang H, Kadam P, Lin Q, Lim T, Singh Sandhu J, et al.
J Proteomics
. 2012 Jul;
75(18):5762-73.
PMID: 22842289
In humans, primitive fetal nucleated red blood cells (FNRBCs) are thought to be as vital for embryonic life as their counterpart, adult red blood cells (adult RBCs) are in later-gestation...
10.
Manikandan J, Kothandaraman N, Hande M, Pushparaj P
Cell Mol Life Sci
. 2011 Dec;
69(12):1917-29.
PMID: 22146792
Allergy and anaphylaxis are inflammatory disorders caused by immune reactions mainly induced by immunoglobulin-E that signal through the high-affinity FcεRI receptor to release the inflammatory mediators from innate immune cells....