Naomi Nakagata
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Explore the profile of Naomi Nakagata including associated specialties, affiliations and a list of published articles.
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206
Citations
3367
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Recent Articles
1.
Ueno E, Watanabe M, Kondo Y, Nakagata N, Takeo T, Nakao S, et al.
iScience
. 2025 Feb;
28(2):111846.
PMID: 39981520
Mice administered an inhibin antiserum, equine chorionic gonadotropin (eCG) mixture called CARD HyperOva (OVA)/human chorionic gonadotropin (hCG), ovulate more oocytes than those administered eCG/hCG. In this study, the mechanism by...
2.
Nakao S, Shirakado K, Tamura K, Koga R, Ikeda-Imafuku M, Ishima Y, et al.
Biol Reprod
. 2024 Dec;
PMID: 39689237
The redox state of thiol groups derived from cysteine residues in proteins regulates cellular functions. Changes in the redox state of thiol groups in the epididymis are involved in sperm...
3.
Ishizuka Y, Nakao S, Kamisako T, Yamaga K, Nakagata N, Ishizaki H, et al.
Sci Rep
. 2024 Oct;
14(1):24198.
PMID: 39406819
The cryopreservation of rat embryos is useful for efficiently archiving rat resources in bioresource repositories. The cryopreserved fertilized oocytes can be quickly reanimated to rats with homozygous mutations using embryo...
4.
Kuroshima S, Nakao S, Horikoshi Y, Ito K, Ishii A, Shirakawa A, et al.
Lab Anim
. 2024 Aug;
58(4):313-323.
PMID: 39102515
Niemann-Pick disease type C (NPC) is a lethal genetic disease with mutations in or gene. -deficient () mice have been used as a model for NPC pathogenesis to develop novel...
5.
Nakamura Y, Watanabe H, Imafuku T, Fujita I, Ganaha Y, Takeo T, et al.
Mol Pharm
. 2024 Jun;
21(7):3144-3150.
PMID: 38862418
α-Acid glycoprotein (AGP) is a primary binding protein for many basic drugs in plasma. The number of drugs that bind to AGP, such as molecular target anticancer drugs, has been...
6.
Yamada Y, Ishitsuka Y, Fukaura-Nishizawa M, Kawata T, Ishii A, Shirakawa A, et al.
Life Sci
. 2024 Jun;
350:122776.
PMID: 38852794
Niemann-Pick disease type C (NPC) is a lysosomal lipid storage disorder characterized by progressive neurodegeneration and hepatic dysfunction. A cyclic heptasaccharide, 2-hydroxypropyl-β-cyclodextrin (HP-β-CD), is currently under clinical investigation for NPC,...
7.
Aisyah R, Ohshima N, Watanabe D, Nakagawa Y, Sakuma T, Nitschke F, et al.
Commun Biol
. 2024 May;
7(1):604.
PMID: 38769369
Glycerophosphocholine (GPC) is an important precursor for intracellular choline supply in phosphatidylcholine (PC) metabolism. GDE5/Gpcpd1 hydrolyzes GPC into choline and glycerol 3-phosphate; this study aimed to elucidate its physiological function...
8.
Yamaga K, Nakao S, Mikoda N, Sztein J, Nakagata N, Takeo T
J Reprod Dev
. 2024 Mar;
70(2):131-137.
PMID: 38432992
Cold transport of the cauda epididymides is a useful technique for shipping laboratory rat sperm. Cold transport of rat sperm avoids potential risks of microbiological infection, animal escape or death,...
9.
Nakagata N, Nakao S, Mikoda N, Yamaga K, Takeo T
J Reprod Dev
. 2024 Feb;
70(2):123-130.
PMID: 38403585
Genetically modified rats are valuable models in human disease research. We recently developed an improved system for rat sperm cryopreservation and in vitro fertilization (IVF) that facilitates the efficient production...
10.
Tsurudome Y, Yoshida Y, Hamamura K, Ogino T, Yasukochi S, Yasuo S, et al.
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38339119
Prostaglandins are bioactive compounds, and the activation of their receptors affects the expression of clock genes. However, the prostaglandin F receptor () has no known relationship with biological rhythms. Here,...