Naohiro Inohara
Overview
Explore the profile of Naohiro Inohara including associated specialties, affiliations and a list of published articles.
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107
Citations
10592
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Recent Articles
1.
Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface
Mansoori Moghadam Z, Zhao B, Raynaud RWTH University Hospital C, Strohmeier V, Neuber J, Losslein A, et al.
Blood
. 2025 Feb;
PMID: 39899882
Controlled development of cellular intestinal immunity in the face of dynamic microbiota emergence constitutes a major challenge in very early life, and a bottleneck for sustained growth and well-being. Early-onset...
2.
Yamazaki Y, Ito T, Nakagawa S, Sugihira T, Kurita-Tachibana C, Villaruz A, et al.
Nat Commun
. 2024 Nov;
15(1):9619.
PMID: 39511195
Staphylococcus aureus can cause outbreaks and becomes multi-drug resistant through gene mutations and acquiring resistance genes. However, why S. aureus easily adapts to hospital environments, promoting resistance and recurrent infections,...
3.
Guo Y, Kitamoto S, Caballero-Flores G, Kim Y, Watanabe D, Sugihara K, et al.
Gut Microbes
. 2024 Mar;
16(1):2333463.
PMID: 38545880
The ectopic gut colonization by orally derived pathobionts has been implicated in the pathogenesis of various gastrointestinal diseases, including inflammatory bowel disease (IBD). For example, gut colonization by orally derived...
4.
Sanidad K, Rager S, Carrow H, Ananthanarayanan A, Callaghan R, Hart L, et al.
Sci Immunol
. 2024 Mar;
9(93):eadj4775.
PMID: 38489352
The gut microbiota promotes immune system development in early life, but the interactions between the gut metabolome and immune cells in the neonatal gut remain largely undefined. Here, we demonstrate...
5.
Aoyama R, Nakagawa S, Ichikawa Y, Inohara N, Yamazaki Y, Ito T, et al.
Allergy
. 2024 Mar;
79(6):1618-1622.
PMID: 38459797
No abstract available.
6.
Lo B, Kryczek I, Yu J, Vatan L, Caruso R, Matsumoto M, et al.
Science
. 2024 Jan;
383(6678):62-70.
PMID: 38175892
Immune checkpoint inhibitors can stimulate antitumor immunity but can also induce toxicities termed immune-related adverse events (irAEs). Colitis is a common and severe irAE that can lead to treatment discontinuation....
7.
Kuffa P, Pickard J, Campbell A, Yamashita M, Schaus S, Martens E, et al.
Cell Host Microbe
. 2023 Nov;
31(12):2007-2022.e12.
PMID: 37967555
Exclusive enteral nutrition (EEN) with fiber-free diets is an effective steroid-sparing treatment to induce clinical remission in children with Crohn's disease (CD). However, the mechanism underlying the beneficial effects of...
8.
Nakatsuka Y, Matsumoto M, Inohara N, Nunez G
Cell Rep
. 2023 Aug;
42(8):112973.
PMID: 37561628
Neutrophils play a critical role in the eradication of Pseudomonas aeruginosa, a major pathogen causing lung infection. However, the mechanisms used by the pathogen to evade neutrophil-mediated killing remain poorly...
9.
Ribeiro A, Jiao Y, Girnary M, Alves T, Chen L, Farrell A, et al.
Mol Oral Microbiol
. 2022 Oct;
37(6):256-265.
PMID: 36189827
Objectives: We have previously characterized the main osteoimmunological events that occur during ligature periodontitis. This study aims to determine the polymicrobial community shifts that occur during disease development. Methods: Periodontitis...
10.
Yamazaki S, Inohara N, Ohmuraya M, Tsuneoka Y, Yagita H, Katagiri T, et al.
Mucosal Immunol
. 2022 Aug;
15(6):1321-1337.
PMID: 35999460
Control of gut microbes is crucial for not only local defense in the intestine but also proper systemic immune responses. Although intestinal epithelial cells (IECs) play important roles in cytokine-mediated...