Nancy M Dahms
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Explore the profile of Nancy M Dahms including associated specialties, affiliations and a list of published articles.
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47
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1238
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Recent Articles
1.
Kanack A, Prodoehl E, Ishihara-Aoki M, Aoki K, Dahms N
Sci Rep
. 2024 Nov;
14(1):29488.
PMID: 39604471
Fabry disease is an X-linked lysosomal storage disorder caused by deficiency of the lysosomal enzyme ⍺-galactosidase-A (⍺-Gal A), resulting in widespread accumulation of terminal galactose-containing glycosphingolipids (GSLs) and the impairment...
2.
Bohnsack R, Misra S, Liu J, Ishihara-Aoki M, Pereckas M, Aoki K, et al.
Sci Rep
. 2024 Nov;
14(1):26875.
PMID: 39505925
The cation-independent mannose 6-phosphate receptor (CI-MPR) is clinically significant in the treatment of patients with lysosomal storage diseases because it functions in the biogenesis of lysosomes by transporting mannose 6-phosphate...
3.
Waltz T, Chao D, Prodoehl E, Enders J, Ehlers V, Dharanikota B, et al.
JCI Insight
. 2024 Apr;
9(8).
PMID: 38646936
Patients with Fabry disease suffer from chronic debilitating pain and peripheral sensory neuropathy with minimal treatment options, but the cellular drivers of this pain are unknown. Here, we propose a...
4.
Waltz T, Chao D, Prodoehl E, Ehlers V, Dharanikota B, Dahms N, et al.
bioRxiv
. 2023 Jun;
PMID: 37292928
Patients with Fabry disease suffer from chronic debilitating pain and peripheral sensory neuropathy with minimal treatment options, but the cellular drivers of this pain are unknown. Here, we propose a...
5.
Yang C, Barbieri J, Dahms N, Chen C
Biochemistry
. 2022 Mar;
61(7):616-624.
PMID: 35285627
is an opportunistic pathogen producing many immune evasion molecules targeting various components of the host immune defense, including the Staphylococcal superantigen-like protein (SSL 1-14) family. Despite sharing similar structures with...
6.
Kanack A, Aoki K, Tiemeyer M, Dahms N
FASEB J
. 2021 Jul;
35(8):e21818.
PMID: 34320241
Fabry disease results from a deficiency of the lysosomal enzyme ⍺-Galactosidase-A (⍺-Gal A) and is estimated to occur in approximately 1:4100 live births. Characteristic of the disease is the accumulation...
7.
Miller J, Bohnsack R, Olson L, Ishihara M, Aoki K, Tiemeyer M, et al.
Sci Rep
. 2021 Apr;
11(1):8213.
PMID: 33859256
Plasmin is the key enzyme in fibrinolysis. Upon interaction with plasminogen activators, the zymogen plasminogen is converted to active plasmin. Some studies indicate plasminogen activation is regulated by cation-independent mannose...
8.
Beltrame A, Dahms N, Runge C
Biosci Rep
. 2021 Jan;
41(2).
PMID: 33506259
The present study examined auditory function across age in the dark agouti (DA) rat strain. Auditory brainstem responses (ABRs) were measured for frequencies 8, 16, and 32 kHz in male...
9.
Olson L, Misra S, Ishihara M, Battaile K, Grant O, Sood A, et al.
Commun Biol
. 2020 Sep;
3(1):498.
PMID: 32908216
The cation-independent mannose 6-phosphate receptor (CI-MPR, IGF2 receptor or CD222), is a multifunctional glycoprotein required for normal development. Through the receptor's ability to bind unrelated extracellular and intracellular ligands, it...
10.
Miller J, Kanack A, Dahms N
Biochim Biophys Acta Gen Subj
. 2019 Sep;
1864(1):129437.
PMID: 31526868
Background: Fabry disease is caused by α-galactosidase A deficiency. Substrates of this lysosomal enzyme accumulate, resulting in cellular dysfunction. Patients experience neuropathic pain, kidney failure, heart disease, and strokes. Scope...