Nancy L Craig
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Explore the profile of Nancy L Craig including associated specialties, affiliations and a list of published articles.
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Recent Articles
21.
Arensburger P, Hice R, Zhou L, Smith R, Tom A, Wright J, et al.
Genetics
. 2011 Mar;
188(1):45-57.
PMID: 21368277
Transposons are found in virtually all organisms and play fundamental roles in genome evolution. They can also acquire new functions in the host organism and some have been developed as...
22.
Yusa K, Zhou L, Li M, Bradley A, Craig N
Proc Natl Acad Sci U S A
. 2011 Jan;
108(4):1531-6.
PMID: 21205896
DNA transposons have been widely used for transgenesis and insertional mutagenesis in various organisms. Among the transposons active in mammalian cells, the moth-derived transposon piggyBac is most promising with its...
23.
Gangadharan S, Mularoni L, Fain-Thornton J, Wheelan S, Craig N
Proc Natl Acad Sci U S A
. 2010 Dec;
107(51):21966-72.
PMID: 21131571
Transposons are mobile genetic elements that are an important source of genetic variation and are useful tools for genome engineering, mutagenesis screens, and vectors for transgenesis including gene therapy. We...
24.
Mitra R, McKenzie G, Yi L, Lee C, Craig N
Mob DNA
. 2010 Jul;
1(1):18.
PMID: 20653944
The bacterial transposon Tn7 is distinguished by its ability to recognize a specific site called attTn7, and insert just downstream of the highly conserved chromosomal glmS gene. TnsD is one...
25.
Holder J, Craig N
J Mol Biol
. 2010 Jun;
401(2):167-81.
PMID: 20538004
Four transposition proteins encoded by the bacterial transposon Tn7, TnsA, TnsB, TnsC, and TnsD, mediate its site- and orientation-specific insertion into the chromosomal site attTn7. To establish which Tns proteins...
26.
27.
Mitra R, Fain-Thornton J, Craig N
EMBO J
. 2008 Mar;
27(7):1097-109.
PMID: 18354502
DNA synthesis is considered a defining feature in the movement of transposable elements. In determining the mechanism of piggyBac transposition, an insect transposon that is being increasingly used for genome...
28.
Ray D, Feschotte C, Pagan H, Smith J, Pritham E, Arensburger P, et al.
Genome Res
. 2008 Mar;
18(5):717-28.
PMID: 18340040
DNA transposons, or class 2 transposable elements, have successfully propagated in a wide variety of genomes. However, it is widely believed that DNA transposon activity has ceased in mammalian genomes...
29.
Evertts A, Plymire C, Craig N, Levin H
Genetics
. 2007 Oct;
177(4):2519-23.
PMID: 17947404
Currently, no transposon-based method for the mutagenesis of Schizosaccharomyces pombe exists. We have developed such a system based on the introduction of the hermes transposon from the housefly into S....
30.
McKenzie G, Craig N
BMC Microbiol
. 2006 May;
6:39.
PMID: 16646962
Background: Inserting transgenes into bacterial chromosomes is generally quite involved, requiring a selection for cells carrying the insertion, usually for drug-resistance, or multiple cumbersome manipulations, or both. Several approaches use...