Nancy L Craig
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Explore the profile of Nancy L Craig including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Choi K, Li Y, Sarnovsky R, Craig N
Proc Natl Acad Sci U S A
. 2013 May;
110(22):E2038-45.
PMID: 23674682
The transposon Tn7 transposase that recognizes the transposon ends and mediates breakage and joining is heteromeric. It contains the Tn7-encoded proteins TnsB, which binds specifically to the transposon ends and...
12.
Burnight E, Staber J, Korsakov P, Li X, Brett B, Scheetz T, et al.
Mol Ther Nucleic Acids
. 2013 Jan;
1:e50.
PMID: 23344650
Nonviral vector systems are used increasingly in gene targeting and gene transfer applications. The piggyBac transposon represents an alternative integrating vector for in vivo gene transfer. We hypothesized that this...
13.
Mitra R, Li X, Kapusta A, Mayhew D, Mitra R, Feschotte C, et al.
Proc Natl Acad Sci U S A
. 2012 Dec;
110(1):234-9.
PMID: 23248290
A revelation of the genomic age has been the contributions of the mobile DNA segments called transposable elements to chromosome structure, function, and evolution in virtually all organisms. Substantial fractions...
14.
Woodard L, Li X, Malani N, Kaja A, Hice R, Atkinson P, et al.
PLoS One
. 2012 Nov;
7(11):e42666.
PMID: 23166581
Background: Transposons are useful tools for creating transgenic organisms, insertional mutagenesis, and genome engineering. TcBuster, a novel hAT-family transposon system derived from the red flour beetle Tribolium castaneum, was shown...
15.
Li X, Ewis H, Hice R, Malani N, Parker N, Zhou L, et al.
Proc Natl Acad Sci U S A
. 2012 Oct;
110(6):E478-87.
PMID: 23091042
Chromosome structure and function are influenced by transposable elements, which are mobile DNA segments that can move from place to place. hAT elements are a superfamily of DNA cut and...
16.
Hencken C, Li X, Craig N
Nat Struct Mol Biol
. 2012 Jul;
19(8):834-6.
PMID: 22773102
The formation of diverse immunoglobulin genes results in part from Rag protein-mediated DNA double-strand breaks at the edges of immunoglobulin gene segments, followed by combinatorial reassembly of these segments. We...
17.
Green B, Bouchier C, Fairhead C, Craig N, Cormack B
Mob DNA
. 2012 Feb;
3(1):3.
PMID: 22313799
Background: Transposons, segments of DNA that can mobilize to other locations in a genome, are often used for insertion mutagenesis or to generate priming sites for sequencing of large DNA...
18.
Arensburger P, Hice R, Wright J, Craig N, Atkinson P
BMC Genomics
. 2011 Dec;
12:606.
PMID: 22171608
Background: The piRNA pathway has been shown in model organisms to be involved in silencing of transposons thereby providing genome stability. In D. melanogaster the majority of piRNAs map to...
19.
Doherty J, Huye L, Yusa K, Zhou L, Craig N, Wilson M
Hum Gene Ther
. 2011 Oct;
23(3):311-20.
PMID: 21992617
We characterized a recently developed hyperactive piggyBac (pB) transposase enzyme [containing seven mutations (7pB)] for gene transfer in human cells in vitro and to somatic cells in mice in vivo....
20.
Li M, Turner D, Ning Z, Yusa K, Liang Q, Eckert S, et al.
Nucleic Acids Res
. 2011 Sep;
39(22):e148.
PMID: 21948799
The development of technologies that allow the stable delivery of large genomic DNA fragments in mammalian systems is important for genetic studies as well as for applications in gene therapy....