Nancy E Wickersham
Overview
Explore the profile of Nancy E Wickersham including associated specialties, affiliations and a list of published articles.
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12
Citations
277
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Recent Articles
1.
Rizzo A, Haeger S, Oshima K, Yang Y, Wallbank A, Jin Y, et al.
JCI Insight
. 2021 Dec;
7(2).
PMID: 34874923
Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure yet has few pharmacologic therapies, reflecting the mechanistic heterogeneity of lung injury. We hypothesized that damage to the...
2.
Bastarache J, McNeil J, Plosa E, Sucre J, Kerchberger V, Habegger L, et al.
Am J Physiol Lung Cell Mol Physiol
. 2021 Mar;
320(5):L785-L790.
PMID: 33655765
Noninvasive sampling of the distal airspace in patients with acute respiratory distress syndrome (ARDS) has long eluded clinical and translational researchers. We recently reported that fluid collected from heat moisture...
3.
Yu W, McNeil J, Wickersham N, Shaver C, Bastarache J, Ware L
Crit Care
. 2021 Feb;
25(1):48.
PMID: 33541396
Background: Endothelial dysfunction and injury is a major pathophysiologic feature of sepsis. Sepsis is also the most frequent cause of acute kidney injury (AKI) in critically ill patients. Though most...
4.
Kerchberger V, Bastarache J, Shaver C, Nagata H, McNeil J, Landstreet S, et al.
JCI Insight
. 2019 Oct;
4(21).
PMID: 31573976
Acute respiratory distress syndrome (ARDS) is an inflammatory lung disorder that frequently complicates critical illness and commonly occurs in sepsis. Although numerous clinical and environmental risk factors exist, not all...
5.
Yu W, McNeil J, Wickersham N, Shaver C, Bastarache J, Ware L
Crit Care
. 2019 Jan;
23(1):18.
PMID: 30658667
Background: Vascular endothelial cadherin (VE-cadherin) is a membrane protein that is the major component of adherens junctions between endothelial cells. It is crucial for regulating vascular integrity, endothelial permeability, and...
6.
McNeil J, Shaver C, Kerchberger V, Russell D, Grove B, Warren M, et al.
Am J Respir Crit Care Med
. 2017 Dec;
197(8):1027-1035.
PMID: 29253353
Rationale: A major barrier to a more complete understanding of acute respiratory distress syndrome (ARDS) pathophysiology is the inability to sample the distal airspace of patients with ARDS. The heat...
7.
Shaver C, Woods J, Clune J, Grove B, Wickersham N, McNeil J, et al.
Crit Care
. 2017 May;
21(1):120.
PMID: 28545548
Background: It is unclear how to identify which patients at risk for acute respiratory distress syndrome (ARDS) will develop this condition during critical illness. Elevated microparticle (MP) concentrations in the...
8.
Shaver C, Upchurch C, Janz D, Grove B, Putz N, Wickersham N, et al.
Am J Physiol Lung Cell Mol Physiol
. 2016 Jan;
310(6):L532-41.
PMID: 26773065
Patients with the acute respiratory distress syndrome (ARDS) have elevated levels of cell-free hemoglobin (CFH) in the air space, but the contribution of CFH to the pathogenesis of acute lung...
9.
Ma L, Shaver C, Grove B, Mitchell D, Wickersham N, Carnahan R, et al.
Clin Transl Med
. 2015 Jul;
4(1):63.
PMID: 26154059
Background: Activation of coagulation by expression of tissue factor (TF) in the airspace is a hallmark of acute lung injury (ALI) but the timing of TF activation in relationship to...
10.
Parr S, Clark A, Bian A, Shintani A, Wickersham N, Ware L, et al.
Kidney Int
. 2014 Sep;
87(3):640-8.
PMID: 25229339
Biomarker studies for early detection of acute kidney injury (AKI) have been limited by nonselective testing and uncertainties in using small changes in serum creatinine as a reference standard. Here...