Julie A Bastarache
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Explore the profile of Julie A Bastarache including associated specialties, affiliations and a list of published articles.
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113
Citations
2388
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Recent Articles
1.
Davis Puente A, Davis A, Johnson D, Bastarache J
BMJ Open Respir Res
. 2025 Mar;
10(1).
PMID: 40042935
Introduction: Immune checkpoint inhibitors (ICI) have improved outcomes for patients with many malignancies. However, these treatments are associated with immune-related adverse events, including pulmonary toxicity (pneumonitis). Pneumonitis is associated with...
2.
Stier M, Sewell A, Mwizerwa E, Sim C, Tanner S, Nichols C, et al.
bioRxiv
. 2025 Feb;
PMID: 39975258
Host immunity in sepsis has features of hyperinflammation together with progressive immunosuppression, particularly among CD4 T cells, that can predispose to secondary infections and ineffectual organ recovery. Metabolic and immunologic...
3.
Shimoda L, Bastarache J, Britt Jr R, Kuebler W
Am J Physiol Lung Cell Mol Physiol
. 2025 Jan;
328(3):L321-L323.
PMID: 39823196
No abstract available.
4.
Meegan J, Rizzo A, Schmidt E, Bastarache J
Clin Chest Med
. 2024 Oct;
45(4):821-833.
PMID: 39443000
The alveolar-capillary barrier includes microvascular endothelial and alveolar epithelial cells and their matrices, and its disruption is a critical driver of lung injury during development of acute respiratory distress syndrome....
5.
Bogart A, Lopez C, Obeidalla S, Wang C, Willmore A, Jauregui A, et al.
CHEST Crit Care
. 2024 Oct;
2(3).
PMID: 39421542
Background: Only a subset of patients at risk for ARDS go on to develop it, and the contribution of preexisting comorbidities (eg, diabetes) to ARDS risk is not well understood....
6.
Schaaf K, Landstreet S, Putz N, Gonski S, Lin J, Buggs C, et al.
PLoS One
. 2024 Sep;
19(9):e0308648.
PMID: 39312544
Background: The alveolar epithelium is protected by a heparan sulfate-rich, glycosaminoglycan layer called the epithelial glycocalyx. It is cleaved in patients with acute respiratory distress syndrome (ARDS) and in murine...
7.
Kerchberger V, McNeil J, Zheng N, Chang D, Rosenberger C, Rogers A, et al.
medRxiv
. 2024 Sep;
PMID: 39252926
Background: Large population-based DNA biobanks linked to electronic health records (EHRs) may provide novel opportunities to identify genetic drivers of ARDS. Research Question: Can we develop an EHR-based algorithm to...
8.
Hough R, Alvira C, Bastarache J, Erzurum S, Kuebler W, Schmidt E, et al.
Am J Respir Cell Mol Biol
. 2024 Aug;
71(4):388-406.
PMID: 39189891
Lung endothelium resides at the interface between the circulation and the underlying tissue, where it senses biochemical and mechanical properties of both the blood as it flows through the vascular...
9.
Murphy M, Yang Z, Subati T, Farber-Eger E, Kim K, Blackwell D, et al.
Cardiovasc Res
. 2024 Feb;
120(8):899-913.
PMID: 38377486
Aims: The lymphocyte adaptor protein (LNK) is a negative regulator of cytokine and growth factor signalling. The rs3184504 variant in SH2B3 reduces LNK function and is linked to cardiovascular, inflammatory,...
10.
Kuhar E, Chander N, Stewart D, Jahandideh F, Zhang H, Kristof A, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Feb;
326(6):L661-L671.
PMID: 38349120
It is unclear what effect biological sex has on outcomes of acute lung injury (ALI). Clinical studies are confounded by their observational design. We addressed this knowledge gap with a...