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Nancy C Elliott

Explore the profile of Nancy C Elliott including associated specialties, affiliations and a list of published articles. Areas
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Citations 24
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Recent Articles
1.
McClure K, Letavic M, Kalgutkar A, Gabel C, Audoly L, Barberia J, et al.
Bioorg Med Chem Lett . 2006 Jun; 16(16):4339-44. PMID: 16759861
The synthesis, structure-activity relationship, in vivo activity, and metabolic profile for a series of triazolopyridine-oxazole based p38 inhibitors are described. The deficiencies of the lead structure in the series, CP-808844,...
2.
McClure K, Abramov Y, Laird E, Barberia J, Cai W, Carty T, et al.
J Med Chem . 2005 Sep; 48(18):5728-37. PMID: 16134941
Mimics of the benzimidazolone nucleus found in inhibitors of p38 kinase are proposed, and their theoretical potential as bioisosteres is described. A set of calculated descriptors relevant to the anticipated...
3.
Blagg J, Noe M, Wolf-Gouveia L, Reiter L, Laird E, Chang S, et al.
Bioorg Med Chem Lett . 2005 Mar; 15(7):1807-10. PMID: 15780611
Through the use of computational modeling, a series of pyrimidinetrione-based inhibitors of MMP-13 was designed based on a lead inhibitor identified through file screening. Incorporation of a biaryl ether moiety...
4.
Pekala R, Maurer R, Kumar V, Elliott N, Masten E, Moon E, et al.
Am J Clin Hypn . 2004 Jun; 46(4):281-97. PMID: 15190730
This study evaluated the effectiveness of a self-hypnosis protocol with chronic drug and alcohol patients in increasing self-esteem, improving affect, and preventing relapse against a control, a transtheoretical cognitive-behavioral (TCB),...
5.
Dombroski M, Letavic M, McClure K, Barberia J, Carty T, Cortina S, et al.
Bioorg Med Chem Lett . 2004 Mar; 14(4):919-23. PMID: 15012994
The synthesis and in vitro p38 alpha activity of a novel series of benzimidazolone inhibitors is described. The p38 alpha SAR is consistent with a mode of binding wherein the...