Nagham Alatrash
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Explore the profile of Nagham Alatrash including associated specialties, affiliations and a list of published articles.
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11
Citations
61
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Recent Articles
1.
Mutore K, Koduri R, Alatrash N, Nomellini V
Shock
. 2024 Aug;
62(4):461-469.
PMID: 39178216
Although there have been numerous advancements in burn wound management, burn injuries are still a major cause of morbidity and mortality in the United States, and novel therapeutics are still...
2.
Wu R, Koduri R, Cho M, Alatrash N, Nomellini V
Brain Behav Immun Health
. 2024 Apr;
38:100762.
PMID: 38590762
Traumatic Brain Injury (TBI) is a major cause of severe disability and death, resulting in significant health care and economic burden. Poloxamer 188, a synthetic tri-block copolymer approved by the...
3.
Reardon M, Guerrero M, Alatrash N, MacDonnell F
ChemMedChem
. 2023 Aug;
18(21):e202300347.
PMID: 37574460
Ruthenium(II) trisdiimine complexes of the formula, [Ru(dip) (L-L) ] , where n=0-3; dip=4,7-diphenyl-1,10-phenanthroline; L-L=2,2'-bipyridine (bpy) or 1,10-phenanthroline (phen) were prepared and tested for cytotoxicity in two cell lines (H358, MCF7)....
4.
Handlovic T, Wahab M, Cole H, Alatrash N, Ramasamy E, MacDonnell F, et al.
Anal Chim Acta
. 2022 Sep;
1228:340156.
PMID: 36126998
Sub/supercritical fluid chromatography (SFC) is a green separation technique that has been used to separate a wide variety of compounds and is proven to be immensely useful for chiral separations....
5.
Alatrash N, Issa F, Bawazir N, West S, Van Manen-Brush K, Shelor C, et al.
Chem Sci
. 2021 May;
11(1):264-275.
PMID: 34040721
Treatment of malignant and non-malignant cultured human cell lines with a cytotoxic IC dose of ∼2 μM tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(ii) chloride () retards or arrests microtubule motion as tracked by visualizing fluorescently-tagged...
6.
Aslan J, Reardon M, Alatrash N, Nastasi F, MacDonnell F
Photochem Photobiol
. 2021 Apr;
98(1):42-48.
PMID: 33896014
Dipyridophenazine (dppz) is known to react with alcohols upon photoexcitation into an n-π* transition at 378 nm to yield dihydrodipyridophenazine (dppzH ). This process occurs via H-atom abstraction from alcohols...
7.
Du S, Sung Y, Wey M, Wang Y, Alatrash N, Berthod A, et al.
Mol Biol Rep
. 2020 Sep;
47(9):6749-6758.
PMID: 32892308
N-methyl-D-aspartate (NMDA) receptors, which are widely present in the central nervous system, have also been found to be up-regulated in a variety of cancer cells and tumors and they can...
8.
Du S, Wang Y, Alatrash N, Weatherly C, Roy D, MacDonnell F, et al.
J Pharm Biomed Anal
. 2018 Nov;
164:421-429.
PMID: 30445355
Herein we describe for the first time the endogenous levels of free l-and d-amino acids in cultured human breast cancer cells (MCF-7) and non-tumorigenic human breast epithelial cells (MCF-10A). d-Asp...
9.
Alatrash N, Narh E, Yadav A, Kim M, Janaratne T, Gabriel J, et al.
ChemMedChem
. 2017 Jun;
12(13):1055-1069.
PMID: 28605571
Four mononuclear [(L-L) Ru(tatpp)] and two dinuclear [(L-L) Ru(tatpp)Ru(L-L) ] ruthenium(II) polypyridyl complexes (RPCs) containing the 9,11,20,22-tetraazatetrapyrido[3,2-a:2',3'-c:3'',2''-l:2''',3'''-n]pentacene (tatpp) ligand were synthesized, in which L-L is a chelating diamine ligand such...
10.
Griffith C, Dayoub A, Jaranatne T, Alatrash N, Mohamedi A, Abayan K, et al.
Chem Sci
. 2017 May;
8(5):3726-3740.
PMID: 28553531
The ruthenium(ii) polypyridyl complexes (RPCs), [(phen)Ru(tatpp)] ( ) and [(phen)Ru(tatpp)Ru(phen)] ( ) are shown to cleave DNA in cell-free studies in the presence of a mild reducing agent, glutathione (GSH),...