Frederick M MacDonnell
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Explore the profile of Frederick M MacDonnell including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
221
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Recent Articles
1.
Reardon M, Guerrero M, Alatrash N, MacDonnell F
ChemMedChem
. 2023 Aug;
18(21):e202300347.
PMID: 37574460
Ruthenium(II) trisdiimine complexes of the formula, [Ru(dip) (L-L) ] , where n=0-3; dip=4,7-diphenyl-1,10-phenanthroline; L-L=2,2'-bipyridine (bpy) or 1,10-phenanthroline (phen) were prepared and tested for cytotoxicity in two cell lines (H358, MCF7)....
2.
Handlovic T, Wahab M, Cole H, Alatrash N, Ramasamy E, MacDonnell F, et al.
Anal Chim Acta
. 2022 Sep;
1228:340156.
PMID: 36126998
Sub/supercritical fluid chromatography (SFC) is a green separation technique that has been used to separate a wide variety of compounds and is proven to be immensely useful for chiral separations....
3.
Alatrash N, Issa F, Bawazir N, West S, Van Manen-Brush K, Shelor C, et al.
Chem Sci
. 2021 May;
11(1):264-275.
PMID: 34040721
Treatment of malignant and non-malignant cultured human cell lines with a cytotoxic IC dose of ∼2 μM tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(ii) chloride () retards or arrests microtubule motion as tracked by visualizing fluorescently-tagged...
4.
Aslan J, Reardon M, Alatrash N, Nastasi F, MacDonnell F
Photochem Photobiol
. 2021 Apr;
98(1):42-48.
PMID: 33896014
Dipyridophenazine (dppz) is known to react with alcohols upon photoexcitation into an n-π* transition at 378 nm to yield dihydrodipyridophenazine (dppzH ). This process occurs via H-atom abstraction from alcohols...
5.
Du S, Sung Y, Wey M, Wang Y, Alatrash N, Berthod A, et al.
Mol Biol Rep
. 2020 Sep;
47(9):6749-6758.
PMID: 32892308
N-methyl-D-aspartate (NMDA) receptors, which are widely present in the central nervous system, have also been found to be up-regulated in a variety of cancer cells and tumors and they can...
6.
Du S, Wang Y, Alatrash N, Weatherly C, Roy D, MacDonnell F, et al.
J Pharm Biomed Anal
. 2018 Nov;
164:421-429.
PMID: 30445355
Herein we describe for the first time the endogenous levels of free l-and d-amino acids in cultured human breast cancer cells (MCF-7) and non-tumorigenic human breast epithelial cells (MCF-10A). d-Asp...
7.
Alatrash N, Narh E, Yadav A, Kim M, Janaratne T, Gabriel J, et al.
ChemMedChem
. 2017 Jun;
12(13):1055-1069.
PMID: 28605571
Four mononuclear [(L-L) Ru(tatpp)] and two dinuclear [(L-L) Ru(tatpp)Ru(L-L) ] ruthenium(II) polypyridyl complexes (RPCs) containing the 9,11,20,22-tetraazatetrapyrido[3,2-a:2',3'-c:3'',2''-l:2''',3'''-n]pentacene (tatpp) ligand were synthesized, in which L-L is a chelating diamine ligand such...
8.
Griffith C, Dayoub A, Jaranatne T, Alatrash N, Mohamedi A, Abayan K, et al.
Chem Sci
. 2017 May;
8(5):3726-3740.
PMID: 28553531
The ruthenium(ii) polypyridyl complexes (RPCs), [(phen)Ru(tatpp)] ( ) and [(phen)Ru(tatpp)Ru(phen)] ( ) are shown to cleave DNA in cell-free studies in the presence of a mild reducing agent, glutathione (GSH),...
9.
Chanmanee W, Islam M, Dennis B, MacDonnell F
Proc Natl Acad Sci U S A
. 2016 Feb;
113(10):2579-84.
PMID: 26903631
A one-step, gas-phase photothermocatalytic process for the synthesis of hydrocarbons, including liquid alkanes, aromatics, and oxygenates, with carbon numbers (Cn) up to C13, from CO2 and water is demonstrated in...
10.
Aslan J, Boston D, MacDonnell F
Chemistry
. 2015 Oct;
21(48):17314-23.
PMID: 26448144
Four derivatives of the laminate acceptor ligand dipyrido-[3,2-a:2',3'-c]phenazine (dppz) and their corresponding ruthenium complexes, [Ru(phen)2 (dppzX2 )](2+) , were prepared and characterized by NMR spectroscopy, ESI-MS, and elemental analysis. The...