Nadine Haetscher
Overview
Explore the profile of Nadine Haetscher including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
234
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0
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Recent Articles
1.
Malkomes P, Lunger I, Oppermann E, Abou-El-Ardat K, Oellerich T, Gunther S, et al.
Oncogene
. 2021 Jun;
40(25):4352-4367.
PMID: 34103685
Despite a high clinical need for the treatment of colorectal carcinoma (CRC) as the second leading cause of cancer-related deaths, targeted therapies are still limited. The multifunctional enzyme Transglutaminase 2...
2.
Bhayadia R, Krowiorz K, Haetscher N, Jammal R, Emmrich S, Obulkasim A, et al.
J Clin Oncol
. 2018 Feb;
36(10):1007-1016.
PMID: 29432078
Purpose Dysregulated microRNAs are implicated in the pathogenesis and aggressiveness of acute myeloid leukemia (AML). We describe the effect of the hematopoietic stem-cell self-renewal regulating miR-193b on progression and prognosis...
3.
Mohr S, Doebele C, Comoglio F, Berg T, Beck J, Bohnenberger H, et al.
Cancer Cell
. 2017 Apr;
31(4):549-562.e11.
PMID: 28399410
The transcription factor Meis1 drives myeloid leukemogenesis in the context of Hox gene overexpression but is currently considered undruggable. We therefore investigated whether myeloid progenitor cells transformed by Hoxa9 and...
4.
Malkomes P, Lunger I, Luetticke A, Oppermann E, Haetscher N, Serve H, et al.
Ann Surg Oncol
. 2016 Apr;
23(9):2849-57.
PMID: 27059026
Background: Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. Growing evidence indicates that tumor-initiating cells (TICs) are responsible for tumor growth and progression. Conventional chemotherapeutics do not...
5.
Wingert S, Thalheimer F, Haetscher N, Rehage M, Schroeder T, Rieger M
Stem Cells
. 2016 Jan;
34(3):699-710.
PMID: 26731607
Hematopoietic stem cells (HSCs) maintain blood cell production life-long by their unique abilities of self-renewal and differentiation into all blood cell lineages. Growth arrest and DNA-damage-inducible 45 alpha (GADD45A) is...
6.
Haetscher N, Feuermann Y, Wingert S, Rehage M, Thalheimer F, Weiser C, et al.
Nat Commun
. 2015 Nov;
6:8928.
PMID: 26603207
Haematopoietic stem cells (HSCs) require the right composition of microRNAs (miR) for proper life-long balanced blood regeneration. Here we show a regulatory circuit that prevents excessive HSC self-renewal by upregulation...
7.
Cytokine-regulated GADD45G induces differentiation and lineage selection in hematopoietic stem cells
Thalheimer F, Wingert S, De Giacomo P, Haetscher N, Rehage M, Brill B, et al.
Stem Cell Reports
. 2014 Jul;
3(1):34-43.
PMID: 25068120
The balance of self-renewal and differentiation in long-term repopulating hematopoietic stem cells (LT-HSC) must be strictly controlled to maintain blood homeostasis and to prevent leukemogenesis. Hematopoietic cytokines can induce differentiation...
8.
Feuermann Y, Kang K, Gavrilova O, Haetscher N, Jang S, Yoo K, et al.
RNA Biol
. 2013 Dec;
10(12):1807-14.
PMID: 24356587
Generating heat and maintaining body temperature is the primary function of brown adipose tissue (BAT). Previous studies have implicated microRNAs, including miR-193b and miR-365-1, in BAT differentiation. We used mouse...