Nabil J Alkayed
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Explore the profile of Nabil J Alkayed including associated specialties, affiliations and a list of published articles.
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124
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2872
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Recent Articles
11.
Bah T, Siler D, Ibrahim A, Cetas J, Alkayed N
Neurobiol Dis
. 2023 Jan;
177:105986.
PMID: 36603747
Recent human and animal model experimental studies revealed novel pathways for fluid movement, immune cell trafficking and metabolic waste clearance in CNS. These studies raise the intriguing possibility that the...
12.
Ohashi S, DeLong J, Kozberg M, Mazur-Hart D, van Veluw S, Alkayed N, et al.
Stroke
. 2023 Jan;
54(2):605-619.
PMID: 36601948
Hemorrhagic stroke is the deadliest form of stroke and includes the subtypes of intracerebral hemorrhage and subarachnoid hemorrhage. A common cause of hemorrhagic stroke in older individuals is cerebral amyloid...
13.
Davis C, Lyon-Scott K, Varlamov E, Zhang W, Alkayed N
Int J Mol Sci
. 2022 Oct;
23(20).
PMID: 36293020
STAT3 plays a protective role against ischemic brain injury; however, it is not clear which brain cell type mediates this effect, and by which mechanism. We tested the hypothesis that...
14.
Xu Y, Zhang W, Allen E, Fedorov L, Barnes A, Qian Z, et al.
Transl Stroke Res
. 2022 Oct;
14(5):766-775.
PMID: 36181628
No current treatments target microvascular reperfusion after stroke, which can contribute to poor outcomes even after successful clot retrieval. The G protein-coupled receptor GPR39 is expressed in brain peri-capillary pericytes,...
15.
Davis C, Zhang W, Bah T, Roese N, Allen E, Leung P, et al.
NPJ Aging
. 2022 Aug;
8(1):9.
PMID: 35927273
Soluble epoxide hydrolase (sEH) is upregulated in microvascular endothelium of human brain with vascular cognitive impairment (VCI). Transgenic endothelial expression of human sEH in mice (Tie2hsEH) induces endothelial dysfunction (ED),...
16.
Bah T, Allen E, Garcia-Jaramillo M, Perez R, Zarnegarnia Y, Davis C, et al.
Front Cell Neurosci
. 2022 Jul;
16:893030.
PMID: 35875352
Vascular cognitive impairment (VCI) is the second most common cause of dementia. There is no treatment for VCI, in part due to a lack of understanding of the underlying mechanisms....
17.
18.
Cao Z, Minnier J, Liu L, Scott K, Reddy A, Wilmarth P, et al.
Sci Rep
. 2022 May;
12(1):8835.
PMID: 35614104
The microcirculation serves crucial functions in adult heart, distinct from those carried out by epicardial vessels. Microvessels are governed by unique regulatory mechanisms, impairment of which leads to microvessel-specific pathology....
19.
Alkayed N, Cao Z, Qian Z, Nagarajan S, Liu X, Nelson J, et al.
Am J Physiol Cell Physiol
. 2022 Apr;
322(5):C1011-C1021.
PMID: 35385329
Arachidonic acid metabolites epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates (HETEs) are important regulators of myocardial blood flow and coronary vascular resistance (CVR), but their mechanisms of action are not fully understood. We...
20.
Azarbal A, Repella T, Carlson E, Manalo E, Palanuk B, Vatankhah N, et al.
Vasc Endovascular Surg
. 2021 Dec;
56(3):244-252.
PMID: 34961389
Objective: Tobacco smoke exposure is a major risk factor for aortic aneurysm development. However, the initial aortic response to tobacco smoke, preceding aneurysm formation, is not well understood. We sought...