N Z M Homer
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Explore the profile of N Z M Homer including associated specialties, affiliations and a list of published articles.
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6
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21
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Recent Articles
1.
Gifford R, Taylor N, Carroll A, Sweeting J, Parsons I, Stacey M, et al.
BMJ Mil Health
. 2024 Apr;
PMID: 38604756
Introduction: Measuring cortisol during military training offers insights into physiological responses to stress. We attempted precisely timed, cortisol awakening response (CAR) and pre-sleep cortisol (PSC), and diurnal slope (peak morning...
2.
Khan S, Livingstone D, Zielinska A, Doig C, Cobice D, Esteves C, et al.
J Endocrinol
. 2023 Jun;
258(3).
PMID: 37343234
11β-Hydroxysteroid dehydrogenase 1 (11βHSD1) is a drug target to attenuate adverse effects of chronic glucocorticoid excess. It catalyses intracellular regeneration of active glucocorticoids in tissues including brain, liver and adipose...
3.
Bode E, Markby G, Boag A, Martinez-Pereira Y, Corcoran B, Farquharson C, et al.
Vet J
. 2020 Jun;
258:105456.
PMID: 32564866
The enzyme 11-beta-hydroxysteroid dehydrogenase isoenzyme 2 (11BHSD2) is responsible for converting the active glucocorticoid cortisol to inactive cortisone and in the renal medulla protects the mineralocorticoid receptor (MR) from activation...
4.
Gifford R, OLeary T, Double R, Wardle S, Wilson K, Boyle L, et al.
Psychoneuroendocrinology
. 2019 Sep;
110:104432.
PMID: 31536944
Background: Basic military training (BMT) is a useful model of prolonged exposure to multiple stressors. 8-12 week BMT is associated with perturbations in the hypothalamic-pituitary-adrenal (HPA) axis which could predispose...
5.
Agnew E, Garcia-Burgos A, Richardson R, Manos H, Thomson A, Sooy K, et al.
J Endocrinol
. 2019 Apr;
241(3):279-292.
PMID: 31013474
Endogenous glucocorticoid action is important in the structural and functional maturation of the fetal heart. In fetal mice, although glucocorticoid concentrations are extremely low before E14.5, glucocorticoid receptor (GR) is...
6.
Wilson K, Mole D, Binnie M, Homer N, Zheng X, Yard B, et al.
Protein Expr Purif
. 2013 Dec;
95:96-103.
PMID: 24316190
Kynurenine 3-monooxygenase (KMO) is an enzyme central to the kynurenine pathway of tryptophan metabolism. KMO has been implicated as a therapeutic target in several disease states, including Huntington's disease. Recombinant...