N T Nashed
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Explore the profile of N T Nashed including associated specialties, affiliations and a list of published articles.
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12
Citations
183
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Recent Articles
1.
Louis J, Wondrak E, Kimmel A, Wingfield P, Nashed N
J Biol Chem
. 1999 Aug;
274(33):23437-42.
PMID: 10438521
Previously it was demonstrated using a model precursor that processing at the N terminus of the HIV-1 protease (PR) precedes processing at its C terminus. We now show the expression,...
2.
Louis J, Dyda F, Nashed N, Kimmel A, Davies D
Biochemistry
. 1998 Mar;
37(8):2105-10.
PMID: 9485357
The HIV-1 transframe region (TFR) is between the structural and functional domains of the Gag-Pol polyprotein, flanked by the nucleocapsid and the protease domains at its N and C termini,...
3.
A transient precursor of the HIV-1 protease. Isolation, characterization, and kinetics of maturation
Wondrak E, Nashed N, Haber M, Jerina D, Louis J
J Biol Chem
. 1996 Feb;
271(8):4477-81.
PMID: 8626801
Recently, the mechanism of autoprocessing of the protease (PR) of the human immunodeficiency virus type 1 from the model polyprotein, MBP-DeltaTF-PR-DeltaPol, which contains the protease linked to short native flanking...
4.
Louis J, Nashed N, Parris K, Kimmel A, Jerina D
Proc Natl Acad Sci U S A
. 1994 Aug;
91(17):7970-4.
PMID: 8058744
Upon renaturation, the polyprotein MBP-delta TF-Protease-delta Pol, consisting of HIV-1 protease and short native sequences from the trans-frame protein (delta TF) and the polymerase (delta Pol) fused to the maltose-binding...
5.
Chandler P, Pennington M, Maccecchini M, Nashed N, Skolnick P
J Biol Chem
. 1993 Aug;
268(23):17173-8.
PMID: 8349604
Conantokins-T and -G are highly conserved polypeptides derived from Conus venoms. The N-methyl-D-aspartate (NMDA) antagonist properties of these compounds have been attributed to a potent noncompetitive inhibition of polyamine responses....
6.
Baillon J, Nashed N, Kumar A, Wilson S, Jerina D
New Biol
. 1991 Oct;
3(10):1015-9.
PMID: 1722701
No abstract available.
7.
Louis J, McDonald R, Nashed N, Wondrak E, Jerina D, Oroszlan S, et al.
Eur J Biochem
. 1991 Jul;
199(2):361-9.
PMID: 2070793
Various constructs of the human immunodeficiency virus, type 1 (HIV-1) protease containing flanking Pol region sequences were expressed as fusion proteins with the maltose-binding protein of the malE gene of...
8.
Baillon J, Nashed N, Sayer J, Jerina D
Proc Natl Acad Sci U S A
. 1991 Feb;
88(3):1014-8.
PMID: 1704125
Progress of DNA- and/or RNA-directed DNA polymerization reactions can be measured continuously using circular dichroism (CD) or ultraviolet (UV) spectroscopy. In the presence of the Klenow fragment of Escherichia coli...
9.
Nashed N, Louis J, Sayer J, Wondrak E, Mora P, Oroszlan S, et al.
Biochem Biophys Res Commun
. 1989 Sep;
163(2):1079-85.
PMID: 2551268
Ac-Lys-Ala-Ser-Gln-Asn-Phe(NO2)-Pro-Val-Val-NH2 (peptide I) and Thr-Phe-Gln-Ala-Phe(NO2)-Pro-Leu-Arg-Glu-Ala (peptide II) undergo hydrolysis between the p-nitrophenylalanyl and prolyl residues catalyzed by the proteases of HIV-1 and AMV, respectively. The specific hydrolyses of peptides I...
10.
Nashed N, Michaud D, Levin W, Jerina D
J Biol Chem
. 1986 Feb;
261(6):2510-3.
PMID: 3949731
7-Dehydrocholesterol 5,6 beta-oxide covalently modifies and inactivates the rat liver microsomal enzyme cholesterol oxide hydrolase. The covalent modification is presumed to occur at the active site of the enzyme since...